Abstract
Proteomics applications to study the molecular effects of drug administration (pharmacoproteomics) on left ventricular hypertrophy (LVH) and atherosclerosis are here reviewed. In most cases, an absence of complete normalization after treatment is revealed, in contrast to what is reported by classical approaches.
Keywords: Atherosclerosis, cardiac hypertrophy, proteomics, pharmacoproteomics
Cardiovascular & Hematological Disorders-Drug Targets
Title: Pharmacoproteomics in Cardiac Hypertrophy and Atherosclerosis
Volume: 9 Issue: 2
Author(s): Alberto Lazaro, Gloria Alvarez-Llamas, Julio Gallego-Delgado, Fernando de la Cuesta, Julio Osende, Ma Eugenia G. Barderas and Fernando Vivanco
Affiliation:
Keywords: Atherosclerosis, cardiac hypertrophy, proteomics, pharmacoproteomics
Abstract: Proteomics applications to study the molecular effects of drug administration (pharmacoproteomics) on left ventricular hypertrophy (LVH) and atherosclerosis are here reviewed. In most cases, an absence of complete normalization after treatment is revealed, in contrast to what is reported by classical approaches.
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Cite this article as:
Lazaro Alberto, Alvarez-Llamas Gloria, Gallego-Delgado Julio, de la Cuesta Fernando, Osende Julio, Barderas G. Ma Eugenia and Vivanco Fernando, Pharmacoproteomics in Cardiac Hypertrophy and Atherosclerosis, Cardiovascular & Hematological Disorders-Drug Targets 2009; 9 (2) . https://dx.doi.org/10.2174/187152909788488672
DOI https://dx.doi.org/10.2174/187152909788488672 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
Call for Papers in Thematic Issues
Effective Lowering pf Lipoprotein (a) – A new Frontier in Cardiovascular Risk Reduction
Elevated lipoprotein(a) (Lp[a]) is a genetically determined cardiovascular risk factor, causally linked to both atherosclerotic coronary artery disease and aortic valve stenosis. Elevated Lp(a) is widely prevalent, and several cardiovascular societies now recommend performing Lp(a) screening at least once in all adults. While, there are currently no approved drugs aimed ...read more
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