Abstract
1-Thiosugars and their glycosides play crucial roles in carbohydrate chemistry, primarily due to their stability and potential for mimicking O-glycosides. The synthetic methodologies for thioglycosides pose ongoing challenges. In recent years, researchers have shown a growing interest in exploring the applications of thiosugars in various fields, including the development of natural product derivatives, oligo- and polysaccharide mimics, metallodrugs, and dendrimers. Numerous approaches and protocols have been devised for the synthesis of thiosugars. This review aims to comprehensively cover the efforts towards preparing thiosugars and their application as synthetic precursors.
Keywords: Thiosugars, thioglycosides, glycoconjugates, carbohydrates, glycodendrimers, metallodrugs, glucosinolates.
Current Organic Chemistry
Title:1-Thiosugars: From Synthesis to Applications
Volume: 29 Issue: 5
Author(s): Surabhi Gupta and Charles Gauthier*
Affiliation:
- Unité Mixte de Recherche (UMR) INRS-UQAC, Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Chicoutimi, Laval, H7V 1B7, Québec, Canada
Keywords: Thiosugars, thioglycosides, glycoconjugates, carbohydrates, glycodendrimers, metallodrugs, glucosinolates.
Abstract: 1-Thiosugars and their glycosides play crucial roles in carbohydrate chemistry, primarily due to their stability and potential for mimicking O-glycosides. The synthetic methodologies for thioglycosides pose ongoing challenges. In recent years, researchers have shown a growing interest in exploring the applications of thiosugars in various fields, including the development of natural product derivatives, oligo- and polysaccharide mimics, metallodrugs, and dendrimers. Numerous approaches and protocols have been devised for the synthesis of thiosugars. This review aims to comprehensively cover the efforts towards preparing thiosugars and their application as synthetic precursors.
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Cite this article as:
Gupta Surabhi and Gauthier Charles*, 1-Thiosugars: From Synthesis to Applications, Current Organic Chemistry 2025; 29 (5) . https://dx.doi.org/10.2174/0113852728314452240524112438
DOI https://dx.doi.org/10.2174/0113852728314452240524112438 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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