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Current Gene Therapy

Editor-in-Chief

ISSN (Print): 1566-5232
ISSN (Online): 1875-5631

Mini-Review Article

Acetylresveratrol (AC-Res): An Evolving Frontier in Modulating Gene Expression

In Press, (this is not the final "Version of Record"). Available online 10 June, 2024
Author(s): Uttam Prasad Panigrahy, Rahul Subhash Buchade, Sandhya S, Anoop Kumar N, Sachinkumar Dnyaneshwar Gunjal, E. Selvakumari, Narendra Kumar Pandey and Ankita Wal*
Published on: 10 June, 2024

DOI: 10.2174/0115665232291487240603093218

Price: $95

Abstract

Background: Acetylresveratrol (AC-Res), to date, is a powerful stilbene phytoalexin generated organically or as a component of a plant's defensive system, is a significant plant phenolic chemical portion and is investigated as a therapy option for a number of disorders. Owing to its inadequate stabilisation and considerable conformation rigidity, the utility of AC-Res as a medication is limited.

Objective: The current review article outlined the structure of AC-Res, their methods of activity, and the latest technological progress in the administration of these molecules. It is conceivable to deduce that AC-Res has a variety of consequences for the cellular functions of infected cells.

Methods: The literature survey for the present article was gathered from the authentic data published by various peer-reviewed publishers employing Google Scholar and PubMedprioritizing Scopus and Web of Science indexed journals as the search platform focusing on AC-Res pharmacological actions, particularly in the English language.

Result: Despite its extensive spectrum of biological and therapeutic applications, AC-Res has become a source of increasing concern. Depending on the researchers, AC-Res possesses radioprotective, cardioprotective, neurological, anti-inflammatory, and anti-microbial potential. It also has anti-cancer and antioxidant properties.

Conclusion: To avoid non-specific cytotoxicity, optimization efforts are presently emphasizing the possible usage of AC-Res based on nanocrystals, nanoparticles and dendrimers, and nanocrystals. Finally, while using AC-Res in biology is still a way off, researchers agree that if they continue to explore it, AC-Res and similar parts will be recognized as actual possibilities for a variety of things in the next years.

Keywords: Acetyl resveratrol, anticancer, Alzheimer's , antioxidant, neuroprotective, anti-inflammatory.


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