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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential

In Press, (this is not the final "Version of Record"). Available online 07 June, 2024
Author(s): Youness Boukharsa*, Khalid Karrouchi, Houda Attjioui and Muhammed Ansar
Published on: 07 June, 2024

DOI: 10.2174/0113895575287746240528072330

Price: $95

Abstract

Pyridazinones are classical molecules that occupy an important place in heterocyclic chemistry, and since their discovery, they have been widely developed. The introduction of new functional groups into pyridazinone structures has enabled the synthesis of a large diversity of compounds. The pharmacological and agrochemical importance of pyridazinone derivatives has aroused the interest of chemists and directed their research toward the synthesis of new compounds with the aim of improving their biological effectiveness. In this review, we have compiled and discussed the different synthetic routes, reactivity, and pharmacological and agrochemical applications of the pyridazinone ring.

Keywords: Heterocyclic chemistry, pyridazinone, pharmacological activities.


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