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Endocrine, Metabolic & Immune Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

Mini-Review Article

The “Magnificent Seven” in Oral and Systemic Health against COVID-19

Author(s): Marina Di Domenico, Alessandro Motta, Tommaso Dai Prà, Stefania Cantore*, Mario Dioguardi, Eugenia Rosalinda Zanella*, Roberto Arrigoni, Danila De Vito and Filiberto Mastrangelo

Volume 25, Issue 4, 2025

Published on: 24 May, 2024

Page: [271 - 280] Pages: 10

DOI: 10.2174/0118715303296892240506100532

Price: $65

Abstract

The COVID-19 pandemic impacted all areas of daily life, including medical care. Unfortunately, to date, no specific treatments have been found for the cure of this disease, and therefore, it is advisable to implement all possible strategies to prevent infection. In this context, it is important to better define the role of all behaviors, in particular nutrition, in order to establish whether these can both prevent infection and improve the outcome of the disease in patients with COVID-19. There is sufficient evidence to demonstrate that immune response can be weakened by inadequate nutrition. Nutrition management and treatment are very important to enhance the immune response of an infected person against RNA viral infection. A complete nutritional assessment should include anthropometric, dietary, and laboratorial assessment, as well as a multidisciplinary discussion about the patient's clinical condition. In this way, it is possible to establish an individualized nutritional approach to contribute to improving clinical and nutritional prognoses. From this point of view, diet, through intake of vitamins and trace elements and maintaining adequate functioning of the intestinal barrier, can reduce the severity of the COVID-19 infection. In this study, we provide an overview of the effects of diet on COVID-19 infection in non-cancer patients. This notion needs to be further evaluated, and thus, identification, characterization, and targeting of the right nutrition principles related to the management of patients with COVID-19 are likely to improve outcomes and may prevent the infection or lead to a cure.

Keywords: COVID-19, vitamins, microbiota, nutrition, metabolism, translational medicine.


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