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Current Nanomedicine

Editor-in-Chief

ISSN (Print): 2468-1873
ISSN (Online): 2468-1881

Review Article

Nanoemulgel: An Innovative Carrier for Drug Delivery of Poorly Water-soluble Drugs

Author(s): Prevesh Kumar*, Zaira Hussain, Phool Chandra, Diksha, Varsha Raj, Navneet Verma and Alok Singh

Volume 15, Issue 2, 2025

Published on: 05 April, 2024

Page: [157 - 172] Pages: 16

DOI: 10.2174/0124681873286701240320111432

Price: $65

Abstract

Recently, the delivery of hydrophobic/ poorly water-soluble drugs has been a difficult task. Various approaches have been developed to counter the former and other main issues, such as solubility, bioavailability, etc. However, only a few formulations have successfully addressed the problems and nanoemulgels are a standout among them. The nanoemulgel drug delivery approach combines multiple benefits associated with emulsion and gel technologies to improve active moiety solubility, bioavailability, and longevity. The article discusses the present status of nanoemulgel research and development, including its preparation methods and characterization techniques. Additionally, the possible uses of nanoemulgel in targeted drug delivery and cosmetic/ personal care products are discussed. Overall, nanoemulgel technology has shown significant promise as a novel approach to augment the transport of water-insoluble moieties. With further research as well as development, it is expected to have a substantial impact on the pharmaceutical and cosmetic industries. This inclusive review highlighted the role of nanoemulgels as a promising carrier for drug delivery, with an overview of a few illustrations supporting the cause.

Keywords: Nanoemulgel, topical drug delivery, lipophilic drug, absorption enhancer, permeability, nanocarrier.

Graphical Abstract
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