Abstract
Objective: Persistent genital arousal disorder (PGAD) presents with a constant unwelcome sensation of genital arousal. Moreover, restless genital syndrome (RGS) is one of the restless leg syndrome (RLS) variants.
Case Representation: We aimed to clarify the differences between clinical diagnoses of these two similar conditions. Assessing the circadian pattern of symptoms, the simultaneous presence of RLS and restless bladder syndrome, exacerbation of symptoms with caffeine use, healing with magnesium use, and familial history of RLS helped us with the differentiation between PGAD and RGS.
Conclusion: We propose to rule out the diagnosis of RGS in all patients with PGAD symptoms.
Keywords: Persistent genital arousal disorder (PGAD), restless genital syndrome (RGS), restless leg syndrome (RLS), selective serotonin reuptake inhibitors (SSRIs), restless bladder syndrome, non-sexual stimuli.
[http://dx.doi.org/10.1080/009262301317081115] [PMID: 11441520]
[http://dx.doi.org/10.1258/095646206776253480] [PMID: 16595040]
[http://dx.doi.org/10.1111/j.1743-6109.2008.01114.x] [PMID: 19138358]
[http://dx.doi.org/10.1016/j.sxmr.2018.08.001] [PMID: 30301706]
[http://dx.doi.org/10.1016/j.jsxm.2018.02.007] [PMID: 29609914]
[http://dx.doi.org/10.1016/j.sleep.2014.03.025] [PMID: 25023924]
[http://dx.doi.org/10.2169/internalmedicine.55.6815] [PMID: 27629973]
[http://dx.doi.org/10.1001/jamaneurol.2014.1326] [PMID: 25285600]
[http://dx.doi.org/10.1186/s12883-020-01875-1] [PMID: 32787789]
[http://dx.doi.org/10.1016/j.smrv.2017.03.007] [PMID: 28559087]
[http://dx.doi.org/10.1016/j.jns.2019.116519] [PMID: 31669730]
[http://dx.doi.org/10.17241/smr.2020.00787]
[http://dx.doi.org/10.5664/jcsm.6736] [PMID: 28728619]
[http://dx.doi.org/10.1111/j.1743-6109.2010.02079.x] [PMID: 20955316]
[http://dx.doi.org/10.1016/j.jsxm.2022.03.220] [PMID: 35396171]
[http://dx.doi.org/10.1016/j.jsxm.2021.01.172] [PMID: 33612417]
[http://dx.doi.org/10.1016/j.esxm.2021.100372] [PMID: 34126431]
[http://dx.doi.org/10.1080/0092623X.2017.1321598] [PMID: 28459348]
[http://dx.doi.org/10.1067/mob.2002.125704] [PMID: 12114899]
[http://dx.doi.org/10.1111/ene.12242] [PMID: 24118170]
[http://dx.doi.org/10.1097/lgt.0b013e318153f7d4] [PMID: 18162812]
[http://dx.doi.org/10.1177/0956462413489276] [PMID: 23970620]
[http://dx.doi.org/10.1007/s12011-020-02287-5] [PMID: 32676936]