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Current Clinical Pharmacology


ISSN (Print): 1574-8847
ISSN (Online): 2212-3938

Recent Advances in Obesity Pharmacotherapy

Author(s): Marcos A. Mayer, Christian Hocht, Ana Puyo and Carlos A. Taira

Volume 4, Issue 1, 2009

Page: [53 - 61] Pages: 9

DOI: 10.2174/157488409787236128

Price: $65


Obesity is considered a worldwide epidemic. Weight reduction by means of lifestyle changes is difficult to achieve, and pharmacotherapy is frequently needed. Although all currently approved anti-obesity agents have proven to be effective to achieve some degree of weight reduction and improve cardiometabolic risk factors, different compounds differ in their mechanism of action and safety profile. However, it is still difficult to achieve and maintain therapeutic objectives along time. The aim of the present article is to summarize the main characteristics of available anti-obesity agents and to explore novel agents that may provide significant clinical benefits in the future.

Keywords: Anti-obesity agents, obesity, pharmacotherapy, sibutramine, orlistat, rimonabant

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