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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

NMR Studies of Hydroxy Schiff Bases

Author(s): P. E. Hansen, Z. Rozwadowski and T. Dziembowska

Volume 13, Issue 2, 2009

Page: [194 - 215] Pages: 22

DOI: 10.2174/138527209787193738

Price: $65

Abstract

The review covers the use of chemical shifts, isotope effects on chemical shifts and coupling constants in the description of Schiff bases. o-Hydroxy Schiff bases are often tautomeric and special attention is devoted to this feature. Nuclei in question are 1H, 13C, 15N, 19F and 17O. As well primary as secondary isotope effects are treated. Deuterium isotope effects on 13C and 15N chemical shifts are treated in detail and the theoretical background is dealt with. Finally, various applications of Schiff bases in biology and stereochemistry are discussed.

Keywords: spectroscopy, NMR, Hydroxy Schiff Bases, chemical shifts, stereochemistry

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