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Combinatorial Chemistry & High Throughput Screening


ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Synthetic Applications of Polystyrene-Supported 1,1,3,3-Tetramethylguanidine

Author(s): Alberto Coelho, Abel Crespo, Franco Fernandez, PierFrancesco Biagini, Angela Stefanachi and Eddy Sotelo

Volume 11, Issue 10, 2008

Page: [843 - 847] Pages: 5

DOI: 10.2174/138620708786734253

Price: $65


Several applications of polystyrene-supported 1,1,3,3-tetramethylguanidine (PS-TMG) in synthetic organic chemistry have been explored. This study evidenced the effectiveness and versatility of this new member of the supported guanidine superbases as an attractive candidate to replace the bases usually employed in organic synthesis during the implementation of environmentally friendly preparative processes.

Keywords: Supported reagents, TMG, base

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