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Current Biotechnology

Editor-in-Chief

ISSN (Print): 2211-5501
ISSN (Online): 2211-551X

Mini-Review Article

Insights on Bioactive Peptide-loaded Nanoformulations

Author(s): Venkateshwaran Krishnaswami*, Balakrishnan Natarajan, Saravanakumar Arthanari, Jeseeta Suresh and Nirmal Aranvindaraj

Volume 12, Issue 1, 2023

Published on: 19 January, 2023

Page: [3 - 13] Pages: 11

DOI: 10.2174/2211550112666230104123153

Price: $65

Abstract

In order to tackle multifactorial illnesses, the importance of bioactive peptides in nano drug delivery systems is emphasised. Multifactorial diseases are primarily brought on by protein misfolding. Therefore, pharmaceutical formulations are recommended to deliver a successful treatment. Difficulties hinder its application in delivering raw peptides with poor bioavailability, absorption, and circulation time, making it a difficult assignment for researchers. Recently, bioactive peptides have become increasingly important in therapy. In addition, several bioactive proteins have poor absorption characteristics in the GIT. These issues can be resolved by creating nano-based peptide-based delivery systems that encapsulate, retain, protect, and transport bioactive peptides. The focus of the proposed review paper is to provide an overview of peptides, commercialization concerns, and their related attempts to develop into novel peptide-based nanoformulations.

Keywords: Peptides, bioactive, drug delivery, nanoformulations, multifactorial illnesses, protein misfolding, bioavailability.

Graphical Abstract
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