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Current Green Chemistry

Editor-in-Chief

ISSN (Print): 2213-3461
ISSN (Online): 2213-347X

Review Article

Microwave-assisted Synthesis of Fluorinated Heterocycles

Author(s): Chandra Prakash and Ram Singh*

Volume 9, Issue 3, 2022

Published on: 30 December, 2022

Page: [145 - 161] Pages: 17

DOI: 10.2174/2213346110666221223140653

Price: $65

Abstract

The diverse biological applications of fluorinated heterocycles make them crucial chemical compounds. Several synthetic processes have been developed for their synthesis. Microwave-assisted synthesis has emerged as an important technique for generating fluorinated heterocycles in an ecofriendly and energy-efficient manner. It provides several benefits like less reaction time, high reaction yield, homogeneous heat distribution leading to lower side reaction, and better control of reaction temperature. Recently there has been significant progress in microwave use for heterocycle synthesis. This article discusses the applications of microwave irradiation in the synthesis of oxygen, nitrogen, sulphur, selenium, and phosphorous containing fluorinated heterocycles.

Keywords: Heterocycles, fluorinated compounds, microwave, eco-friendly synthesis, green synthesis, imidazole, indole.

Graphical Abstract
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