Login Register Cart 0
Generic placeholder image

Current Bioactive Compounds

Editor-in-Chief

ISSN (Print): 1573-4072
ISSN (Online): 1875-6646

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Anticoccidial Effect of Iberogol and Sulfaclozine on Broilers Experimentally Infected with Eimeria tenella

Author(s): Mohammad Khodadi, Maryam Rassouli* and Saeideh Naeimi

Volume 19, Issue 4, 2023

Published on: 28 October, 2022

Article ID: e210922209011 Pages: 7

DOI: 10.2174/1573407218666220921094210

Price: $65

Abstract

Background: Coccidiosis is a common infection among birds that is caused by Eimeria spp. (Protozoa, Phylum Apicomplexa). Eimeria is transmitted fecal-orally and replicated in the intestines. Coccidiosis causes economic losses and increases birds’ susceptibility to other diseases.

Methods: In this study, the broilers were experimentally infected by Eimeria tenella and then treated with Sulfaclozine and Iberogol. Birds were randomly divided into 5 groups (21 birds each); I: negative control, II: positive control, III: treated by Iberogol, IV: treated by Sulfaclozine, and V: treated by Iberogol+Sulfaclozine. Twenty-one-day-old chickens were infected by 10000 oocysts/ ml/chicken of E. tenella. Treatments were started 1 day after oocyst observation in thirtyday- old chickens. Treatments continued for 3 days, stopped for 2 days, and again continued for the next 2 days.

Results: The results were compared for OPG (oocyst per gram), AW (average weight), FCR (feed conversion ratio), and mortality rate among different groups. According to statistical analysis, the worst results were observed in the Iberogol group (III) among other treatment groups (IV and V), and the most effective treatment was reported in the Iberogol+Sulfaclozine group (V).

Conclusion: Complex herbal medications, such as Iberogol, can have different activities, but in coccidiosis, its antioxidant and anti-inflammatory effects are more than the anticoccidial effect. Therefore, Iberogol can be used with Sulfaclozine to increase its efficiency.

Keywords: Broiler, coccidiosis, iberogol, herbal medication, sulfonamide, Eimeria tenella.

Graphical Abstract

[1]
Conway, D.P.; McKenzie, M.E. Poultry Coccidiosis Diagnostic and Testing Procedures, 3rd ed; Black Well Publishing: UK, 2007.
[http://dx.doi.org/10.1002/9780470344620]
[2]
Lal, K.; Bromley, E.; Oakes, R.; Prieto, J.H.; Sanderson, S.J.; Kurian, D.; Hunt, L.; Yates, J.R., III; Wastling, J.M.; Sinden, R.E.; Tomley, F.M. Proteomic comparison of four Eimeria tenella life-cycle stages: Unsporulated oocyst, sporulated oocyst, sporozoite and second-generation merozoite. Proteomics, 2009, 9(19), 4566-4576.
[http://dx.doi.org/10.1002/pmic.200900305] [PMID: 19795439]
[3]
Long, P.L.; Tompkins, R.V.; Millard, B.J. Coccidiosis in broilers: Evaluation of infection by the examination of broiler house litter for Oocysts. Avian Pathol., 1975, 4(4), 287-294.
[http://dx.doi.org/10.1080/03079457509353877] [PMID: 18777319]
[4]
Reid, W.M. Coccidiosis.Diseases of Poultry; 7th ed; Hofstad, M.S.; Calnek, B.W.; Helmboldt, C.F.; Reid, W.M.; Yoder, H.W., Eds.; Iowa State Univ. Press: Ames, IA, 1978, p. 784-815.
[5]
McDONALD. V.; Shirley, M.W. Past and future: Vaccination against Eimeria. Parasitology, 2009, 136(12), 1477-1489.
[http://dx.doi.org/10.1017/S0031182009006349] [PMID: 19523251]
[6]
Blake, D.P.; Tomley, F.M. Securing poultry production from the ever-present Eimeria challenge. Trends Parasitol., 2014, 30(1), 12-19.
[http://dx.doi.org/10.1016/j.pt.2013.10.003] [PMID: 24238797]
[7]
Dalloul, R.A.; Lillehoj, H.S. Recent advances in immunomodulation and vaccination strategies against coccidiosis. Avian Dis., 2005, 49(1), 1-8.
[http://dx.doi.org/10.1637/7306-11150R] [PMID: 15839405]
[8]
Gilbert, E.R.; Cox, C.M.; Williams, P.M.; McElroy, A.P.; Dalloul, R.A.; Ray, W.K.; Barri, A.; Emmerson, D.A.; Wong, E.A.; Webb, K.E., Jr Eimeria species and genetic background influence the serum protein profile of broilers with coccidiosis. PLoS One, 2011, 6(1), e14636.
[http://dx.doi.org/10.1371/journal.pone.0014636] [PMID: 21297942]
[9]
Fatoba, A.J.; Adeleke, M.A. Diagnosis and control of chicken coccidiosis: A recent update. J. Parasit. Dis., 2018, 42(4), 483-493.
[http://dx.doi.org/10.1007/s12639-018-1048-1] [PMID: 30538344]
[10]
Eckert, J.; Braun, R.; Shirley, M.W.; Coudert, P. Biotechnology, Guidelines on Techniques in Coccidiosis Research; European Comission: Luxembourg, 1995.
[11]
Godwin, R.M.; Morgan, J.A.T. A molecular survey of Eimeria in chickens across Australia. Vet. Parasitol., 2015, 214(1-2), 16-21.
[http://dx.doi.org/10.1016/j.vetpar.2015.09.030] [PMID: 26467277]
[12]
Quiroz-Castaneda, R.E. Avian Coccidiosis, New Strategies of Treatment. Farm Animals Diseases, Recent Omic Trends and New Strategies of Treatment; Intechopen, 2018.
[http://dx.doi.org/10.5772/intechopen.74008]
[13]
Şentepe, İ.; Eraslan, G. Pharmacokinetic of sulfaclozine in broiler chickens. Food Chem. Toxicol., 2010, 48(1), 448-451.
[http://dx.doi.org/10.1016/j.fct.2009.10.044] [PMID: 19887098]
[14]
Kheirabadi, P.K.; Katadj, K.J.; Bahadoran, S.; da Silva, T.J.A.; Samani, D.A.; Cheraghchi Bashi, M. Comparison of the anticoccidial effect of granulated extract of Artemisia sieberi with monensin in experimental coccidiosis in broiler chickens. Exp. Parasitol., 2014, 141, 129-133.
[http://dx.doi.org/10.1016/j.exppara.2014.03.022] [PMID: 24703975]
[15]
Clarke, L.; Fodey, T.L.; Crooks, S.R.H.; Moloney, M.; O’Mahony, J.; Delahaut, P.; O’Kennedy, R.; Danaher, M. A review of coccidiostats and the analysis of their residues in meat and other food. Meat Sci., 2014, 97(3), 358-374.
[http://dx.doi.org/10.1016/j.meatsci.2014.01.004] [PMID: 24534603]
[16]
Krueger, D.; Gruber, L.; Buhner, S.; Zeller, F.; Langer, R.; Seidl, S.; Michel, K.; Schemann, M. The multi-herbal drug STW 5 Iberogast® has prosecretory action in the human intestine. Neurogastroenterol. Motil., 2009, 21(11), 1203-e110.
[http://dx.doi.org/10.1111/j.1365-2982.2008.01242.x] [PMID: 19210628]
[17]
Michael, S.; Kelber, O.; Hauschildt, S.; Spanel-Borowski, K.; Nieber, K. Inhibition of inflammation-induced alterations in rat small intestine by the herbal preparations STW 5 and STW 6. Phytomedicine, 2009, 16(2-3), 161-171.
[http://dx.doi.org/10.1016/j.phymed.2008.10.011] [PMID: 19196500]
[18]
Rahimi, R.; Abdollahi, M. Herbal medicines for the management of irritable bowel syndrome: A comprehensive review. World J. Gastroenterol., 2012, 18(7), 589-600.
[http://dx.doi.org/10.3748/wjg.v18.i7.589] [PMID: 22363129]
[19]
Aviagen broiler management handbook; Scotland, UK, 2018. Available from: https://en.aviagen.com/assets/Tech_Center/Ross_Broiler/Ross-BroilerHandbook2018-EN.pdf
[20]
Aviagen broiler nutrition specification; Scotland, UK, 2007. Available from: https://www.winmixsoft.com/files/info/Ross_308_Broiler_ Nutrition_Spec.pdf
[21]
Golkar, P.; Moattar, F. Essential oil composition, bioactive compounds, and antioxidant activities in Iberis amara L. Nat. Prod. Commun., 2019, 14(5), 1934578X1984635.
[http://dx.doi.org/10.1177/1934578X19846355]
[22]
Aćimović, M.G.; Pavlović, S.Đ.; Varga, A.O.; Filipović, V.M.; Cvetković, M.T.; Stanković, J.M.; Čabarkapa, I.S. Chemical composition and antibacterial activity of Angelica archangelica root essential oil. Nat. Prod. Commun., 2017, 12(2), 1934578X1701200.
[http://dx.doi.org/10.1177/1934578X1701200216] [PMID: 30428212]
[23]
Kazemi, M. Chemical composition and antimicrobial activity of essential oil of Matricaria recutita. Int. J. Food Prop., 2015, 18(8), 1784-1792.
[http://dx.doi.org/10.1080/10942912.2014.939660]
[24]
Seidler-Lozykowska, K.; Baranska, M.; Baranski, R.; Krol, D. Raman analysis of caraway (Carum carvi L.) single fruits. Evaluation of essential oil content and its composition. J. Agric. Food Chem., 2010, 58(9), 5271-5275.
[http://dx.doi.org/10.1021/jf100298z] [PMID: 20402506]
[25]
Chambers, C.S. Holečková, V.; Petrásková, L.; Biedermann, D.; Valentová, K.; Buchta, M.; Křen, V. The silymarin composition… and why does it matter? Food Res. Int., 2017, 100(Pt 3), 339-353.
[http://dx.doi.org/10.1016/j.foodres.2017.07.017] [PMID: 28964357]
[26]
Fernández, I.M.; Ribeiro, P.R.E.; Maldonado, S.A.S.; Ferraz, V.P.; Alemán, R.S. Chemical composition of essential oil of Melissa officinalis L. and antioxidant activity from Boa Vista-RR, Brazil. Afr. J. Pharm. Pharmacol., 2020, 14(3), 41-45.
[http://dx.doi.org/10.5897/AJPP2020.5121]
[27]
Schmidt, E.; Bail, S.; Buchbauer, G.; Stoilova, I.; Atanasova, T.; Stoyanova, A.; Krastanov, A.; Jirovetz, L. Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha x piperita. Nat. Prod. Commun., 2009, 4(8), 1934578X0900400.
[http://dx.doi.org/10.1177/1934578X0900400819] [PMID: 19768994]
[28]
Parvu, M.; Vlase, L.; Fodorpataki, L.; Parvu, O.; Rosca-Casian, O.; Bartha, C.; Barbu-Tudoran, L.; Parvu, A.E. Chemical composition of Celandine (Chelidonium majus L.) extract and its effects on Botrytis tulipae (Lib.) lind fungus and the tulip. Not. Bot. Horti Agrobot. Cluj-Napoca, 2013, 41(2), 414-426.
[http://dx.doi.org/10.15835/nbha4129077]
[29]
Sharma, V.; Katiyar, A.; Agrawal, R.C. Glycyrrhiza glabra: Chemistry and pharmacological activity; Sweeteners, 2018, pp. 87-100.
[http://dx.doi.org/10.1007/978-3-319-27027-2_21]
[30]
Vermeulen, B.; Peek, H.W.; Remon, J.P.; Landman, W.J.M. Effect of ibuprofen on coccidiosis in broiler chickens. Avian Dis., 2004, 48(1), 68-76.
[http://dx.doi.org/10.1637/7059] [PMID: 15077799]
[31]
Chang, C.L.T.; Chung, C.Y.; Kuo, C.H.; Kuo, T.F.; Yang, C.W.; Yang, W.C. Beneficial effect of Bidens pilosa on body weight gain, food conversion ratio, gut bacteria and coccidiosis in chickens. PLoS One, 2016, 11(1), e0146141.
[http://dx.doi.org/10.1371/journal.pone.0146141] [PMID: 26765226]
[32]
Yang, W.C.; Tien, Y.J.; Chung, C.Y.; Chen, Y.C.; Chiou, W.H.; Hsu, S.Y.; Liu, H.Y.; Liang, C.L.; Chang, C.L.T. Effect of Bidens pilosa on infection and drug resistance of Eimeria in chickens. Res. Vet. Sci., 2015, 98, 74-81.
[http://dx.doi.org/10.1016/j.rvsc.2014.11.002] [PMID: 25440995]
[33]
Pop, L.M.; Varga, E.; Coroian, M. Nedișan, M.E.; Mircean, V.; Dumitrache, M.O.; Farczádi, L.; Fülöp, I.; Croitoru, M.D.; Fazakas, M.; Gyӧrke, A. Efficacy of a commercial herbal formula in chicken experimental coccidiosis. Parasit. Vectors, 2019, 12(1), 343-352.
[http://dx.doi.org/10.1186/s13071-019-3595-4] [PMID: 31300024]
[34]
Habibi, H.; Firouzi, S.; Nili, H.; Razavi, M.; Asadi, S.L.; Daneshi, S. Anticoccidial effects of herbal extracts on Eimeria tenella infection in broiler chickens: In vitro and in vivo study. J. Parasit. Dis., 2016, 40(2), 401-407.
[http://dx.doi.org/10.1007/s12639-014-0517-4] [PMID: 27413312]

Rights & Permissions Print Cite
Article Metrics
23
3
World Immunization Week
© 2024 Bentham Science Publishers | Privacy Policy