Generic placeholder image

Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Perspective

COVID-19 Tests and International Travel: How Long Will You Test Positive for SAR-CoV-2?

Author(s): Kam Lun Hon* and Karen Ka Yan Leung

Volume 19, Issue 1, 2023

Published on: 13 October, 2022

Page: [2 - 5] Pages: 4

DOI: 10.2174/1573398X18666220920120531

Abstract

Coronavirus diseases, from SARS to MERS and now COVID-19, have major implications for the aviation industry and international travels. Although many cities and countries are adopting ‘live with COVID’ strategies, various rules and regulations are still in place. Documents demonstrating COVID-19 vaccination or recovery from the disease have now become a basic requirement to enter many travel destinations, while some still require pre-entry and/or post-arrival testing of COVID-19. Recently, the author’s household became COVID-19 positive in late March 2022, as diagnosed by rapid antigen test (RAT), in Singapore whilst enroute to Hong Kong. This had an immediate knock-on impact on hotel quarantine and travel arrangements. Rapid antigen test (RAT) and Polymerase Chain Reaction (PCR) based tests have been used for quarantine, isolation and international travel purposes. The implications and issues of these tests are discussed. Ideally, a COVID-19 test that is fit for purpose should aim at identifying individuals who are infectious with risk of transmission only. Frequent surveillance with an effective RAT may be a more practical solution to normalize international travel without compromising public safety. Meanwhile, physicians have an important role in counselling anxious and often confused travelers before and during international travels. International travelers should be aware of the implications of these COVID-19 testing results, and plan, schedule and have travel insurance accordingly.

Keywords: COVID-19, SARS, MERS, rapid antigen, polymerase chain reaction.

[1]
Hon KL. Severe respiratory syndromes: Travel history matters. Travel Med Infect Dis 2013; 11(5): 285-7.
[http://dx.doi.org/10.1016/j.tmaid.2013.06.005] [PMID: 23820509]
[2]
Routsias JG, Mavrouli M, Tsoplou P, Dioikitopoulou K, Tsakris A. Diagnostic performance of rapid antigen tests (RATs) for SARS-CoV-2 and their efficacy in monitoring the infectiousness of COVID-19 patients. Sci Rep 2021; 11(1): 22863.
[http://dx.doi.org/10.1038/s41598-021-02197-z] [PMID: 34819567]
[3]
Ghasemi S, Harmooshi NN, Rahim F. Diagnostic utility of antigen detection rapid diagnostic tests for Covid-19: A systematic review and meta-analysis. Diagn Pathol 2022; 17(1): 36.
[http://dx.doi.org/10.1186/s13000-022-01215-6] [PMID: 35414002]
[4]
Wölfel R, Corman VM, Guggemos W, et al. Virological assessment of hospitalized patients with COVID-2019. Nature 2020; 581(7809): 465-9.
[http://dx.doi.org/10.1038/s41586-020-2196-x] [PMID: 32235945]
[5]
Zou L, Ruan F, Huang M, et al. SARS-CoV-2 viral load in upper respiratory specimens of infected patients. N Engl J Med 2020; 382(12): 1177-9.
[http://dx.doi.org/10.1056/NEJMc2001737] [PMID: 32074444]
[6]
Young BE, Ong SWX, Kalimuddin S, et al. Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore. JAMA 2020; 323(15): 1488-94.
[http://dx.doi.org/10.1001/jama.2020.3204] [PMID: 32125362]
[7]
Kujawski SA, Wong KK, Collins JP, et al. Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States. Nat Med 2020; 26(6): 861-8.
[http://dx.doi.org/10.1038/s41591-020-0877-5] [PMID: 32327757]
[8]
Mina MJ, Peto TE, García-Fiñana M, Semple MG, Buchan IE. Clarifying the evidence on SARS-CoV-2 antigen rapid tests in public health responses to COVID-19. Lancet 2021; 397(10283): 1425-7.
[http://dx.doi.org/10.1016/S0140-6736(21)00425-6] [PMID: 33609444]
[9]
Cattelan AM, Sasset L, Zabeo F, et al. Rapid antigen test lumiraDxTM vs. Real time polymerase chain reaction for the diagnosis of SARS-CoV-2 infection: A retrospective cohort study. Int J Environ Res Public Health 2022; 19(7): 3826.
[http://dx.doi.org/10.3390/ijerph19073826] [PMID: 35409513]
[10]
Bollinger M, Saile P, Shapeton AD, Kohl M, Kumle B. Sensitivity of severe acute respiratory syndrome coronavirus type 2 rapid antigen point-of-care tests in vaccinated patients. Eur J Emerg Med 2022; 29(4): 285-90.
[11]
List of mutually recognised COVID-19 laboratory based antigenic assays (Annex III) Available from: https://ec.europa.eu/health/sites/health/files/preparedness_response/docs/common_testingapproach_covid-19_en.pdf (Accessed on: May4, 2022)
[12]
Hon KL, Leung KKY. Elimination, containment, and mitigation of COVID-19: A personal story about international travels. Curr Pediatr Rev 2022. E-pub Ahead of Print.
[http://dx.doi.org/10.2174/1573396318666220823152942]

© 2024 Bentham Science Publishers | Privacy Policy