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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Current Issues and Perspectives in Antimicrobials use in Dental Practice

Author(s): Luigi Santacroce*, Francesca Spirito, Lucrezia Bottalico, Eleonora Lo Muzio, Ioannis Alexandros Charitos, Maria Assunta Potenza, Monica Montagnani and Emilio Jirillo

Volume 28, Issue 35, 2022

Published on: 04 October, 2022

Page: [2879 - 2889] Pages: 11

DOI: 10.2174/1381612828666220920114723

Price: $65

Abstract

The complexity of the use of antimicrobials for dental use (such as antibiotics) is directly related not only to the mode of onset of an oral infection (linked to numerous factors of local causality and comorbidity) but also to the predisposing risk for the general health of the patient with putative serious consequences related to the neck district. The abuse and misuse of antibiotics may lead to resistance to certain bacterial strains. In this regard, the evaluation of the risk/benefit of their use (especially in pregnant women) can be divided into two phases: risk analysis and subsequently risk management for the benefit of the patient for the oral pathology to be prevented or treated, respectively. This study seeks to focus on the issues and management of patients with certain antimicrobials during dental practice, placing special emphasis on new classes of antibiotics.

Keywords: Dentistry, oral microbiota, antibiotics, antibiotic toxicology, antibiotic resistance, antifungals.

[1]
Peterson LR. Currently available antimicrobial agents and their potential for use as monotherapy. Clin Microbiol Infect 2008; 14 (Suppl. 6): 30-45.
[http://dx.doi.org/10.1111/j.1469-0691.2008.02125.x] [PMID: 19040464]
[2]
McDonnell G, Russell AD. Antiseptics and disinfectants: Activity, action, and resistance. Clin Microbiol Rev 1999; 12(1): 147-79.
[http://dx.doi.org/10.1128/CMR.12.1.147] [PMID: 9880479]
[3]
Nagy-Bota MC, Man A, Santacroce L, et al. Essential oils as alternatives for root-canal treatment and infection control against Enterococcus faecalis—a preliminary study. Appl Sci 2021; 11(4): 1422.
[http://dx.doi.org/10.3390/app11041422]
[4]
Santacroce L, Bottalico L, Charitos IA. The impact of COVID-19 on Italy: A lesson for the future. Int J Occup Environ Med 2020; 11(3): 151-2.
[http://dx.doi.org/10.34172/ijoem.2020.1984] [PMID: 32225178]
[5]
Bottalico L, Charitos IA, Potenza MA, Montagnani M, Santacroce L. The war against bacteria, from the past to present and beyond. Expert Rev Anti Infect Ther 2022; 20(5): 681-706.
[http://dx.doi.org/10.1080/14787210.2022.2013809] [PMID: 34874223]
[6]
Santacroce L, Bottalico L, Haxhirexha K, Topi S, Charitos IA. Pre-chemistry concepts and medical therapy among ancient physicians through the pre-socratic philosophers. Endocr Metab Immune Disord Drug Targets 2020; 20(9): 1470-7.
[http://dx.doi.org/10.2174/1871530320666200508115041] [PMID: 32384041]
[7]
Santacroce L, Topi S, Haxhirexha K, Hidri S, Charitos IA, Bottalico L. Medicine and healing in the pre-socratic thought - a brief analysis of magic and rationalism in ancient herbal therapy. Endocr Metab Immune Disord Drug Targets 2021; 21(2): 282-7.
[http://dx.doi.org/10.2174/1871530320666200508113728] [PMID: 32384039]
[8]
Santacroce L, Bottalico L, Topi S, Castellaneta F, Charitos IA. The “Scourge of the Renaissance”. A short review about Treponema pallidum infection. Endocr Metab Immune Disord Drug Targets 2020; 20(3): 335-43.
[http://dx.doi.org/10.2174/1871530319666191009144217] [PMID: 31625831]
[9]
Ramu C, Padmanabhan TV. Indications of antibiotic prophylaxis in dental practice-review. Asian Pac J Trop Biomed 2012; 2(9): 749-54.
[http://dx.doi.org/10.1016/S2221-1691(12)60222-6] [PMID: 23570007]
[10]
Ahmadi H, Ebrahimi A, Ahmadi F. Antibiotic therapy in dentistry. Int J Dent 2021; 2021: 1-10.
[http://dx.doi.org/10.1155/2021/6667624] [PMID: 33574843]
[11]
Brookes ZLS, Bescos R, Belfield LA, Ali K, Roberts A. Current uses of chlorhexidine for management of oral disease: A narrative review. J Dent 2020; 103: 103497.
[http://dx.doi.org/10.1016/j.jdent.2020.103497] [PMID: 33075450]
[12]
Mosca A, Dalfino L, Romanelli F, et al. Effectiveness of colistin with rifampicin and meropenem against colistin-resistant Acinetobacter baumannii strains: An in vitro study. Pharmacophore 2020; 11(2): 1-6.
[13]
Ahmad N, Saad N. Effects of antibiotics on dental implants: A review. J Clin Med Res 2012; 4(1): 1-6.
[http://dx.doi.org/10.4021/jocmr658w] [PMID: 22383920]
[14]
Li X, Kolltveit KM, Tronstad L, Olsen I. Systemic diseases caused by oral infection. Clin Microbiol Rev 2000; 13(4): 547-58.
[http://dx.doi.org/10.1128/CMR.13.4.547] [PMID: 11023956]
[15]
Roberts RM, Hersh AL, Shapiro DJ, Fleming-Dutra KE, Hicks LA. Antibiotic prescriptions associated with dental-related emergency department visits. Ann Emerg Med 2019; 74(1): 45-9.
[http://dx.doi.org/10.1016/j.annemergmed.2018.09.019] [PMID: 30392733]
[16]
Romanelli F, Stolfa S, Morea A, et al. Meropenem/vaborbactam activity in vitro: A new option for Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae treatment. Future Microbiol 2021; 16(16): 1261-6.
[http://dx.doi.org/10.2217/fmb-2021-0007] [PMID: 34674551]
[17]
Gouba N, Raoult D, Drancourt M. Plant and fungal diversity in gut microbiota as revealed by molecular and culture investigations. PLoS One 2013; 8(3): e59474.
[http://dx.doi.org/10.1371/journal.pone.0059474] [PMID: 23555039]
[18]
Turnbaugh PJ, Ley RE, Hamady M, Fraser-Liggett CM, Knight R, Gordon JI. The human microbiome project. Nature 2007; 449(7164): 804-10.
[http://dx.doi.org/10.1038/nature06244] [PMID: 17943116]
[19]
Deo PN, Deshmukh R. Oral microbiome: Unveiling the fundamentals. J Oral Maxillofac Pathol 2019; 23(1): 122-8.
[PMID: 31110428]
[20]
Palmer RJ Jr. Composition and development of oral bacterial communities. Periodontol 2000 2014; 64(1): 20-39.
[http://dx.doi.org/10.1111/j.1600-0757.2012.00453.x] [PMID: 24320954]
[21]
Dewhirst FE, Chen T, Izard J, et al. The human oral microbiome. J Bacteriol 2010; 192(19): 5002-17.
[http://dx.doi.org/10.1128/JB.00542-10] [PMID: 20656903]
[22]
Kazor CE, Mitchell PM, Lee AM, et al. Diversity of bacterial populations on the tongue dorsa of patients with halitosis and healthy patients. J Clin Microbiol 2003; 41(2): 558-63.
[http://dx.doi.org/10.1128/JCM.41.2.558-563.2003] [PMID: 12574246]
[23]
Wade WG. The oral microbiome in health and disease. Pharmacol Res 2013; 69(1): 137-43.
[http://dx.doi.org/10.1016/j.phrs.2012.11.006] [PMID: 23201354]
[24]
Santacroce L, Bottalico L, Mangini F. Dental hygiene procedure in a patient with Giardia lamblia infection. Int J Dent Hyg 2007; 5(3): 187-9.
[http://dx.doi.org/10.1111/j.1601-5037.2007.00240.x] [PMID: 17615029]
[25]
Bassis CM, Tang AL, Young VB, Pynnonen MA. The nasal cavity microbiota of healthy adults. Microbiome 2014; 2(1): 27.
[http://dx.doi.org/10.1186/2049-2618-2-27] [PMID: 25143824]
[26]
Santacroce L, Muzio EL, Bottalico L, et al. Subversion of the oral microbiota and induction of immune-mediated systemic inflammation with special reference to periodontitis. Current knowledge and perspectives. Endocr Metab Immune Disord Drug Targets 2022; 22.
[http://dx.doi.org/10.2174/1871530322666220629101357] [PMID: 35770408]
[27]
Martínez A, Kuraji R, Kapila YL. The human oral virome: Shedding light on the dark matter. Periodontol 2000 2021; 87(1): 282-98.
[http://dx.doi.org/10.1111/prd.12396] [PMID: 34463988]
[28]
Parras-Moltó M, López-Bueno A. Methods for enrichment and sequencing of oral viral assemblages: Saliva, oral mucosa, and dental plaque viromes. Methods Mol Biol 2018; 1838: 143-61.
[http://dx.doi.org/10.1007/978-1-4939-8682-8_11] [PMID: 30128995]
[29]
Ptasiewicz M, Grywalska E, Mertowska P, et al. Armed to the teeth—the oral mucosa immunity system and microbiota. Int J Mol Sci 2022; 23(2): 882.
[http://dx.doi.org/10.3390/ijms23020882] [PMID: 35055069]
[30]
Lee PT, Yamamoto FY, Low CF, Loh JY, Chong CM. Gut immune system and the implications of oral-administered immunoprophylaxis in finfish aquaculture. Front Immunol 2021; 12: 773193.
[http://dx.doi.org/10.3389/fimmu.2021.773193] [PMID: 34975860]
[31]
Sharma N, Bhatia S, Singh Sodhi A, Batra N. Oral microbiome and health. AIMS Microbiol 2018; 4(1): 42-66.
[http://dx.doi.org/10.3934/microbiol.2018.1.42] [PMID: 31294203]
[32]
Santacroce L, Carlaio R, Bottalico L. Does it make sense that diabetes is reciprocally associated with periodontal disease? Endocr Metab Immune Disord Drug Targets 2010; 10(1): 57-70.
[http://dx.doi.org/10.2174/187153010790827975] [PMID: 20001897]
[33]
Irani S, Barati I, Badiei M. Periodontitis and oral cancer - current concepts of the etiopathogenesis. Oncol Rev 2020; 14(1): 465.
[http://dx.doi.org/10.4081/oncol.2020.465] [PMID: 32231765]
[34]
Santacroce L, Cagiano R, Del Prete R, et al. Helicobacter pylori infection and gastric MALTomas: An up-to-date and therapy highlight. Clin Ter 2008; 159(6): 457-62.
[PMID: 19169609]
[35]
Losacco T, Cagiano R, Bottalico L, et al. Our experience in Helicobacter pylori infection and gastric MALToma. Clin Ter 2008; 159(4): 239-42.
[PMID: 18776980]
[36]
Yano Y, Etemadi A, Abnet CC. Microbiome and cancers of the esophagus: A review. Microorganisms 2021; 9(8): 1764.
[http://dx.doi.org/10.3390/microorganisms9081764] [PMID: 34442842]
[37]
Hajishengallis G, Liang S, Payne MA, et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe 2011; 10(5): 497-506.
[http://dx.doi.org/10.1016/j.chom.2011.10.006] [PMID: 22036469]
[38]
Belda-Ferre P, Alcaraz LD, Cabrera-Rubio R, et al. The oral metagenome in health and disease. ISME J 2012; 6(1): 46-56.
[http://dx.doi.org/10.1038/ismej.2011.85] [PMID: 21716308]
[39]
Mager DL, Haffajee AD, Devlin PM, Norris CM, Posner MR, Goodson JM. The salivary microbiota as a diagnostic indicator of oral cancer: A descriptive, non-randomized study of cancer-free and oral squamous cell carcinoma subjects. J Transl Med 2005; 3(1): 27.
[http://dx.doi.org/10.1186/1479-5876-3-27] [PMID: 15987522]
[40]
De Luca F, Shoenfeld Y. The microbiome in autoimmune diseases. Clin Exp Immunol 2018; 195(1): 74-85.
[http://dx.doi.org/10.1111/cei.13158] [PMID: 29920643]
[41]
How KY, Song KP, Chan KG. Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line. Front Microbiol 2016; 7: 53.
[http://dx.doi.org/10.3389/fmicb.2016.00053] [PMID: 26903954]
[42]
Lorenzo D. Oral-gut microbiota and arthritis: Is there an evidence-based axis? J Clin Med 2019; 8(10)https://pubmed.ncbi.nlm.nih.gov/31652577/
[43]
Llarrull LI, Testero SA, Fisher JF, Mobashery S. The future of the β-lactams. Curr Opin Microbiol 2010; 13(5): 551-7.
[http://dx.doi.org/10.1016/j.mib.2010.09.008] [PMID: 20888287]
[44]
Bush K, Bradford PA. β-Lactams and β-lactamase inhibitors: An overview. Cold Spring Harb Perspect Med 2016; 6(8): a025247.
[http://dx.doi.org/10.1101/cshperspect.a025247] [PMID: 27329032]
[45]
Brook I, Wexler HM, Goldstein EJC. Antianaerobic antimicrobials: Spectrum and susceptibility testing. Clin Microbiol Rev 2013; 26(3): 526-46.
[http://dx.doi.org/10.1128/CMR.00086-12] [PMID: 23824372]
[46]
Evans J, Hannoodee M, Wittler M. Amoxicillin clavulanate. StatPearls: Treasure Island, FL 2021.
[47]
Easton J, Noble S, Perry CM. Amoxicillin/clavulanic acid: A review of its use in the management of paediatric patients with acute otitis media. Drugs 2003; 63(3): 311-40.
[http://dx.doi.org/10.2165/00003495-200363030-00005] [PMID: 12534334]
[48]
LiverTox Clinical and Research Information on Drug-Induced Liver Injury. Bethesda, MD: National Institute of Diabetes and Digestive and Kidney Diseases 2012.
[49]
Marshall WF, Blair JE. The cephalosporins. Mayo Clin Proc 1999; 74(2): 187-95.
[http://dx.doi.org/10.4065/74.2.187] [PMID: 10069359]
[50]
Vicente D, Pérez-Trallero E. Tetraciclinas, sulfamidas y metronidazol. Enferm Infecc Microbiol Clin 2010; 28(2): 122-30.
[http://dx.doi.org/10.1016/j.eimc.2009.10.002] [PMID: 20097452]
[51]
Setiawatie EM, Lestari VP, Dyah S. Comparison of anti-bacterial efficacy of photodynamic therapy and doxycycline on Aggregatibacter actinomycetemcomitans. Afr J Infect Dis 2018; 12: 95-103.
[http://dx.doi.org/10.21010/ajid.v12i1S.14] [PMID: 29619438]
[52]
Phillips ME, Eastwood JB, Curtis JR, Gower PE, de Wardener HE. Tetracycline poisoning in renal failure. BMJ 1974; 2(5911): 149-51.
[http://dx.doi.org/10.1136/bmj.2.5911.149] [PMID: 4825113]
[53]
Primosch RE. Tetracycline discoloration, enamel defects, and dental caries in patients with cystic fibrosis. Oral Surg Oral Med Oral Pathol 1980; 50(4): 301-8.
[http://dx.doi.org/10.1016/0030-4220(80)90411-9] [PMID: 6935580]
[54]
Williams JD, Maskell JP, Shain H, et al. Comparative in-vitro activity of azithromycin, macrolides (erythromycin, clarithromycin and spiramycin) and streptogramin RP 59500 against oral organisms. J Antimicrob Chemother 1992; 30(1): 27-37.
[http://dx.doi.org/10.1093/jac/30.1.27] [PMID: 1331019]
[55]
Brittain DC. Erythromycin. Med Clin North Am 1987; 71(6): 1147-54.
[http://dx.doi.org/10.1016/S0025-7125(16)30802-1] [PMID: 3320616]
[56]
Nilius AM, Beyer JM, Flamm RK, Tanaka SK. Variability in susceptibilities of Haemophilus influenzae to clarithromycin and azithromycin due to medium pH. J Clin Microbiol 1997; 35(6): 1311-5.
[http://dx.doi.org/10.1128/jcm.35.6.1311-1315.1997] [PMID: 9163435]
[57]
Charitos IA, Topi S, Gagliano-Candela R, et al. The toxic effects of endocrine disrupting chemicals (EDCs) on gut microbiota: Bisphenol A (BPA). A review. Endocr Metab Immune Disord Drug Targets 2022; 22(7): 716-27.
[http://dx.doi.org/10.2174/1871530322666220325114045] [PMID: 35339192]
[58]
Soper DE. Clindamycin. Obstet Gynecol Clin North Am 1992; 19(3): 483-96.
[http://dx.doi.org/10.1016/S0889-8545(21)00369-7] [PMID: 1436926]
[59]
Smieja M. Current indications for the use of clindamycin: A critical review. Can J Infect Dis 1998; 9(1): 22-8.
[http://dx.doi.org/10.1155/1998/538090] [PMID: 22346533]
[60]
Hernández Ceruelos A, Romero-Quezada LC, Ruvalcaba Ledezma JC, López Contreras L. Therapeutic uses of metronidazole and its side effects: An update. Eur Rev Med Pharmacol Sci 2019; 23(1): 397-401.
[PMID: 30657582]
[61]
Freeman CD, Klutman NE, Lamp KC. Metronidazole. Drugs 1997; 54(5): 679-708.
[http://dx.doi.org/10.2165/00003495-199754050-00003] [PMID: 9360057]
[62]
Aldred KJ, Kerns RJ, Osheroff N. Mechanism of quinolone action and resistance. Biochemistry 2014; 53(10): 1565-74.
[http://dx.doi.org/10.1021/bi5000564] [PMID: 24576155]
[63]
Teoh L, Cheung MC, Dashper S, James R, McCullough MJ. Oral antibiotic for empirical management of acute dentoalveolar infections—a systematic review. Antibiotics 2021; 10(3): 240.
[http://dx.doi.org/10.3390/antibiotics10030240] [PMID: 33670844]
[64]
Rajeswari K, Kandaswamy D, Karthick S. Endodontic management of patients with systemic complications. J Pharm Bioallied Sci 2016; 8 (Suppl. 1): S32-5.
[PMID: 27829742]
[65]
Giudice G, Cutrignelli D, Sportelli P, et al. Rhinocerebral mucormycosis with orosinusal involvement: Diagnostic and surgical treatment guidelines. Endocr Metab Immune Disord Drug Targets 2017; 16(4): 264-9.
[http://dx.doi.org/10.2174/1871530316666161223145055] [PMID: 28017141]
[66]
Fine DH, Hammond BF, Loesche WJ. Clinical use of antibiotics in dental practice. Int J Antimicrob Agents 1998; 9(4): 235-8.
[http://dx.doi.org/10.1016/S0924-8579(98)00003-X] [PMID: 9573493]
[67]
Stein K, Farmer J, Singhal S, Marra F, Sutherland S, Quiñonez C. The use and misuse of antibiotics in dentistry. J Am Dent Assoc 2018; 149(10): 869-884.e5.
[http://dx.doi.org/10.1016/j.adaj.2018.05.034] [PMID: 30261952]
[68]
Murphy EC, Frick IM. Gram-positive anaerobic cocci – commensals and opportunistic pathogens. FEMS Microbiol Rev 2013; 37(4): 520-53.
[http://dx.doi.org/10.1111/1574-6976.12005] [PMID: 23030831]
[69]
Oberoi SS, Dhingra C, Sharma G, Sardana D. Antibiotics in dental practice: How justified are we. Int Dent J 2015; 65(1): 4-10.
[http://dx.doi.org/10.1111/idj.12146] [PMID: 25510967]
[70]
Mangini F, Santacroce L, Bottalico L. Periodontitis and systemic diseases. Clin Ter 2006; 157(6): 541-8.
[PMID: 17228854]
[71]
Maruyama N, Maruyama F, Takeuchi Y, Aikawa C, Izumi Y, Nakagawa I. Intraindividual variation in core microbiota in peri-implantitis and periodontitis. Sci Rep 2015; 4(1): 6602.
[http://dx.doi.org/10.1038/srep06602] [PMID: 25308100]
[72]
Bachtiar BM, Theodorea CF, Tahapary DL, Astrella C. Natalina, Bachtiar EW. A pilot study of red complex and three genera subgingival microbiome in periodontitis subjects with and without diabetes, evaluated by MinION platform. F1000 Res 2021; 10: 79.
[http://dx.doi.org/10.12688/f1000research.28216.3] [PMID: 34249333]
[73]
Rokaya D, Srimaneepong V, Wisitrasameewon W, Humagain M, Thunyakitpisal P. Peri-implantitis update: Risk indicators, diagnosis, and treatment. Eur J Dent 2020; 14(4): 672-82.
[http://dx.doi.org/10.1055/s-0040-1715779] [PMID: 32882741]
[74]
Esposito M, Grusovin MG, Worthington HV. Treatment of peri-implantitis: What interventions are effective? A cochrane systematic review. Eur J Oral Implantology 2012; 5: S21-41.
[PMID: 22834392]
[75]
Bottalico L, Valenzano A, Leone D, Mangini F, Santacroce L. The incidence of dental caries during childhood. A clinical and epidemiologic study in Matera (Southern Italy). Clin Ter 2007; 158(5): 409-19.
[PMID: 18062347]
[76]
van Winkelhoff AJ. Antibiotics in the treatment of peri-implantitis. Eur J Oral Implantology 2012; 5: S43-50.
[PMID: 22834393]
[77]
Herrera D, Sanz M, Jepsen S, Needleman I, Roldán S. A systematic review on the effect of systemic antimicrobials as an adjunct to scaling and root planing in periodontitis patients. J Clin Periodontol 2002; 29 (Suppl. 3): 136-59.
[http://dx.doi.org/10.1034/j.1600-051X.29.s3.8.x] [PMID: 12787214]
[78]
Tamma PD, Cosgrove SE, Maragakis LL. Combination therapy for treatment of infections with gram-negative bacteria. Clin Microbiol Rev 2012; 25(3): 450-70.
[http://dx.doi.org/10.1128/CMR.05041-11] [PMID: 22763634]
[79]
Vila T, Sultan AS, Montelongo-Jauregui D, Jabra-Rizk MA. Oral candidiasis: A disease of opportunity. J Fungi 2020; 6(1): 15.
[http://dx.doi.org/10.3390/jof6010015] [PMID: 31963180]
[80]
Rajendra SAB, Muddana K, Bakki SR. Fungal infections of oral cavity: Diagnosis, management, and association with COVID-19. SN Compr Clin Med 2021; 3(6): 1373-84.
[http://dx.doi.org/10.1007/s42399-021-00873-9] [PMID: 33817556]
[81]
Man A, Ciurea CN, Pasaroiu D, et al. New perspectives on the nutritional factors influencing growth rate of Candida albicans in diabetics. An in vitro study. Mem Inst Oswaldo Cruz 2017; 112(9): 587-92.
[http://dx.doi.org/10.1590/0074-02760170098] [PMID: 28902283]
[82]
Sanitá PV, Vergani CE, Giampaolo ET, Pavarina AC, Machado AL. Growth of Candida species on complete dentures: Effect of microwave disinfection. Mycoses 2009; 52(2): 154-60.
[http://dx.doi.org/10.1111/j.1439-0507.2008.01558.x] [PMID: 18627472]
[83]
Altarawneh S, Bencharit S, Mendoza L, et al. Clinical and histological findings of denture stomatitis as related to intraoral colonization patterns of Candida albicans, salivary flow, and dry mouth. J Prosthodont 2013; 22(1): 13-22.
[http://dx.doi.org/10.1111/j.1532-849X.2012.00906.x] [PMID: 23107189]
[84]
Hedderwick SA, McNeil SA, Lyons MJ, Kauffman CA. Pathogenic organisms associated with artificial fingernails worn by healthcare workers. Infect Control Hosp Epidemiol 2000; 21(8): 505-9.
[http://dx.doi.org/10.1086/501794] [PMID: 10968715]
[85]
Kulak-Ozkan Y, Kazazoglu E, Arikan A. Oral hygiene habits, denture cleanliness, presence of yeasts and stomatitis in elderly people. J Oral Rehabil 2002; 29(3): 300-4.
[http://dx.doi.org/10.1046/j.1365-2842.2002.00816.x] [PMID: 11896849]
[86]
Kruegel J, Miosge N. Basement membrane components are key players in specialized extracellular matrices. Cell Mol Life Sci 2010; 67(17): 2879-95.
[http://dx.doi.org/10.1007/s00018-010-0367-x] [PMID: 20428923]
[87]
Bozdemir E, Yılmaz HH, Orhan H. Oral mucosal lesions and risk factors in elderly dental patients. J Dent Res Dent Clin Dent Prospect 2019; 13(1): 24-30.
[http://dx.doi.org/10.15171/joddd.2019.004] [PMID: 31217915]
[88]
Kotsovilis S, Fourmousis I, Karoussis IK, Bamia C. A systematic review and meta-analysis on the effect of implant length on the survival of rough-surface dental implants. J Periodontol 2009; 80(11): 1700-18.
[http://dx.doi.org/10.1902/jop.2009.090107] [PMID: 19905941]
[89]
Kc Basnyat S, Sapkota B, Shrestha S. Oral hygiene and gingival health in patients with fixed prosthodontic appliances - a six month follow-up. Kathmandu Univ Med J 2015; 13(52): 328-32.
[PMID: 27423283]
[90]
Könsberg R, Axéll T. Treatment of Candida-infected denture stomatitis with a miconazole lacquer. Oral Surg Oral Med Oral Pathol 1994; 78(3): 306-11.
[http://dx.doi.org/10.1016/0030-4220(94)90059-0] [PMID: 7970589]
[91]
Yarborough A, Cooper L, Duqum I, Mendonça G, McGraw K, Stoner L. Evidence regarding the treatment of denture stomatitis. J Prosthodont 2016; 25(4): 288-301.
[http://dx.doi.org/10.1111/jopr.12454] [PMID: 27062660]
[92]
Friedman LA. Oral hygiene for dental implant patients. Tex Dent J 1991; 108(5): 21-23, 29.
[PMID: 1866703]
[93]
Emami E, Kabawat M, Rompre PH, Feine JS. Linking evidence to treatment for denture stomatitis: A meta-analysis of randomized controlled trials. J Dent 2014; 42(2): 99-106.
[http://dx.doi.org/10.1016/j.jdent.2013.11.021] [PMID: 24316341]
[94]
Okuda K, Adachi M, Iijima K. The efficacy of antimicrobial mouth rinses in oral health care. Bull Tokyo Dent Coll 1998; 39(1): 7-14.
[PMID: 9663026]
[95]
Cortelli SC, Costa FO, Rode Sde M, et al. Mouthrinse recommendation for prosthodontic patients. Braz Oral Res 2014; 28(Spec No): S1806-83242014000200201.
[PMID: 25003786]
[96]
Basrani B, Lemonie C. Chlorhexidine gluconate. Aust Endod J 2005; 31(2): 48-52.
[http://dx.doi.org/10.1111/j.1747-4477.2005.tb00221.x] [PMID: 16128251]
[97]
Mitali R, Sabyasachi S, Krishna V, et al. Mouthwashes-an overview of current knowledge. Int J Oral Health Res Rev 2013; 1: 24-8.
[98]
Abello R, Buitrago C, Prate CM, DeVizio W, Bakar SK. Effect of a mouthrinse containing triclosan and a copolymer on plaque formation in the absence of oral hygiene. Am J Dent 1990; 3: S57-61.
[PMID: 2101251]
[99]
Jenkins GN. Review of fluoride research since 1959. Arch Oral Biol 1999; 44(12): 985-92.
[http://dx.doi.org/10.1016/S0003-9969(99)00110-7] [PMID: 10669075]
[100]
Aoba T, Shimazu Y, Taya Y, Soeno Y, Sato K, Miake Y. Fluoride and apatite formation in vivo and in vitro. J Electron Microsc 2003; 52(6): 615-25.
[http://dx.doi.org/10.1093/jmicro/52.6.615] [PMID: 14756250]
[101]
Machiulskiene V, Nyvad B, Baelum V. Preventive effect of tooth decay of sugar-substituted chewing gum. Community Dent Oral Epidemiol 2001; 29(4): 278-88.
[http://dx.doi.org/10.1034/j.1600-0528.2001.290407.x] [PMID: 11515642]
[102]
Söderling E, Isokangas P, Tenovuo J, Mustakallio S, Mäkinen KK. Long-term xylitol consumption and mutans Streptococci in plaque and saliva. Caries Res 1991; 25(2): 153-7.
[http://dx.doi.org/10.1159/000261359] [PMID: 2059978]
[103]
Chaudhry S, Jaiswal R, Sachdeva S. Dental considerations in cardiovascular patients: A practical perspective. Indian Heart J 2016; 68(4): 572-5.
[http://dx.doi.org/10.1016/j.ihj.2015.11.034] [PMID: 27543484]
[104]
Tonetti MS, Van Dyke TE. working group 1 of the joint EFP/AAP workshop. Periodontitis and atherosclerotic cardiovascular disease: Consensus report of the joint EFP/AAP workshop on periodontitis and systemic diseases. J Periodontol 2013; 84(4): S24-9.
[105]
Sharif J, Raja Shahardin R, Sockalingam G. Pattern of antibiotic prophylaxis practice for dental procedures in children with congenital heart disease. J Indian Soc Pedod Prev Dent 2020; 38(2): 126-31.
[http://dx.doi.org/10.4103/JISPPD.JISPPD_235_18] [PMID: 32611857]
[106]
Santacroce L, Cagiano R, Carlaio RG, Del Prete R, Bottalico L. Dentistry oral hygiene and endocarditis. Pathophysiology and prophylactic therapy. Recenti Prog Med 2008; 99(10): 516-21.
[PMID: 19040131]
[107]
Chapple IL, Genco R. Diabetes and periodontal diseases: Consensus report of the Joint EFP/AAP workshop on periodontitis and systemic diseases. J Periodontol 2013; 84(4): S106-12.
[PMID: 23631572]
[108]
Mealey BL, Ocampo GL. Diabetes mellitus and periodontal disease. Periodontol 2000 2007; 44(1): 127-53.
[http://dx.doi.org/10.1111/j.1600-0757.2006.00193.x] [PMID: 17474930]
[109]
Chávarry NG, Vettore MV, Sansone C, Sheiham A. The relationship between diabetes mellitus and destructive periodontal disease: A meta-analysis. Oral Health Prev Dent 2009; 7(2): 107-27.
[PMID: 19583037]
[110]
Borgnakke WS, Ylöstalo PV, Taylor GW, Genco RJ. Effect of periodontal disease on diabetes: Systematic review of epidemiologic observational evidence. J Periodontol 2013; 84(4): S135-52.
[PMID: 23631574]
[111]
Teshome A, Yitayeh A. The effect of periodontal therapy on glycemic control and fasting plasma glucose level in type 2 diabetic patients: Systematic review and meta-analysis. BMC Oral Health 2017; 17(1): 31.
[http://dx.doi.org/10.1186/s12903-016-0249-1] [PMID: 27473177]
[112]
Li H, Wang Y, Zhang D, Chen T, Hu A, Han X. Glycemic fluctuation exacerbates inflammation and bone loss and alters microbiota profile around implants in diabetic mice with experimental peri-implantitis. Int J Implant Dent 2021; 7(1): 79.
[http://dx.doi.org/10.1186/s40729-021-00360-9] [PMID: 34401982]
[113]
Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: A review. Diabetologia 2001; 44(2): 129-46.
[http://dx.doi.org/10.1007/s001250051591] [PMID: 11270668]
[114]
Rizzo A, Losacco A, Carratelli CR, Domenico MD, Bevilacqua N. Lactobacillus plantarum reduces Streptococcus pyogenes virulence by modulating the IL-17, IL-23 and Toll-like receptor 2/4 expressions in human epithelial cells. Int Immunopharmacol 2013; 17(2): 453-61.
[http://dx.doi.org/10.1016/j.intimp.2013.07.005] [PMID: 23892030]
[115]
Ruiz HH, Ramasamy R, Schmidt AM. Advanced glycation end products: Building on the concept of the “common soil” in metabolic disease. Endocrinology 2020; 161(1): bqz006.
[http://dx.doi.org/10.1210/endocr/bqz006] [PMID: 31638645]
[116]
Engebretson S, Kocher T. Evidence that periodontal treatment improves diabetes outcomes: A systematic review and meta-analysis. J Clin Periodontol 2013; 40 (Suppl. 14): S153-63.
[http://dx.doi.org/10.1111/jcpe.12084] [PMID: 23627325]
[117]
Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest 2006; 116(7): 1793-801.
[http://dx.doi.org/10.1172/JCI29069] [PMID: 16823477]
[118]
Shoelson SE. Banking on ATM as a new target in metabolic syndrome. Cell Metab 2006; 4(5): 337-8.
[http://dx.doi.org/10.1016/j.cmet.2006.10.009] [PMID: 17084707]
[119]
Wang TF, Jen IA, Chou C, Lei YP. Effects of periodontal therapy on metabolic control in patients with type 2 diabetes mellitus and periodontal disease: A meta-analysis. Medicine 2014; 93(28): e292.
[http://dx.doi.org/10.1097/MD.0000000000000292] [PMID: 25526470]
[120]
Cao R, Li Q, Wu Q, Yao M, Chen Y, Zhou H. Effect of non-surgical periodontal therapy on glycemic control of type 2 diabetes mellitus: A systematic review and Bayesian network meta-analysis. BMC Oral Health 2019; 19(1): 176.
[http://dx.doi.org/10.1186/s12903-019-0829-y] [PMID: 31387569]
[121]
Ioannou I, Dimitriadis N, Papadimitriou K, Vouros I, Sakellari D, Konstantinidis A. The effect of locally delivered doxycycline in the treatment of chronic periodontitis. A clinical and microbiological cohort study. J Oral Maxillofac Res 2011; 1(4): e1.
[PMID: 24421978]
[122]
Nordström D, Lindy O, Lauhio A, Sorsa T, Santavirta S, Konttinen YT. Anti-collagenolytic mechanism of action of doxycycline treatment in rheumatoid arthritis. Rheumatol Int 1998; 17(5): 175-80.
[http://dx.doi.org/10.1007/s002960050030] [PMID: 9542777]
[123]
Tsalamandris S, Antonopoulos AS, Oikonomou E, et al. The role of inflammation in diabetes: Current concepts and future perspectives. Eur Cardiol 2019; 14(1): 50-9.
[http://dx.doi.org/10.15420/ecr.2018.33.1] [PMID: 31131037]
[124]
Chopra I, Roberts M. Tetracycline antibiotics: Mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol Mol Biol Rev 2001; 65(2): 232-60.
[http://dx.doi.org/10.1128/MMBR.65.2.232-260.2001] [PMID: 11381101]
[125]
Roberts MC. Update on acquired tetracycline resistance genes. FEMS Microbiol Lett 2005; 245(2): 195-203.
[http://dx.doi.org/10.1016/j.femsle.2005.02.034] [PMID: 15837373]
[126]
Grossman TH. Tetracycline antibiotics and resistance. Cold Spring Harb Perspect Med 2016; 6(4): a025387.
[http://dx.doi.org/10.1101/cshperspect.a025387] [PMID: 26989065]
[127]
Nguyen F, Starosta AL, Arenz S, Sohmen D, Dönhöfer A, Wilson DN. Tetracycline antibiotics and resistance mechanisms. Biol Chem 2014; 395(5): 559-75.
[http://dx.doi.org/10.1515/hsz-2013-0292] [PMID: 24497223]
[128]
Aloy B, Launay-Vacher V, Bleibtreu A, et al. Antibiotics and chronic kidney disease: Dose adjustment update for infectious disease clinical practice. Med Mal Infect 2020; 50(4): 323-31.
[http://dx.doi.org/10.1016/j.medmal.2019.06.010] [PMID: 31326299]
[129]
Hartmann B, Czock D, Keller F. Drug therapy in patients with chronic renal failure. Dtsch Arztebl Int 2010; 107(37): 647-55.
[http://dx.doi.org/10.3238/arztebl.2010.0647] [PMID: 20959896]
[130]
Andrade RJ, Tulkens PM. Hepatic safety of antibiotics used in primary care. J Antimicrob Chemother 2011; 66(7): 1431-46.
[http://dx.doi.org/10.1093/jac/dkr159] [PMID: 21586591]
[131]
Björnsson ES. Drug-induced liver injury due to antibiotics. Scand J Gastroenterol 2017; 52(6-7): 617-23.
[http://dx.doi.org/10.1080/00365521.2017.1291719] [PMID: 28276834]
[132]
Patel VC, Williams R. Antimicrobial resistance in chronic liver disease. Hepatol Int 2020; 14(1): 24-34.
[http://dx.doi.org/10.1007/s12072-019-10004-1] [PMID: 31797303]
[133]
Dykewicz MS, Lam JK. Drug hypersensitivity reactions. Med Clin North Am 2020; 104(1): 109-28.
[http://dx.doi.org/10.1016/j.mcna.2019.09.003] [PMID: 31757230]
[134]
Devchand M, Trubiano JA. Penicillin allergy: A practical approach to assessment and prescribing. Aust Prescr 2019; 42(6): 192-9.
[http://dx.doi.org/10.18773/austprescr.2019.065] [PMID: 31937989]
[135]
Fraimow H. Systemic antimicrobial therapy in osteomyelitis. Semin Plast Surg 2009; 23(2): 90-9.
[http://dx.doi.org/10.1055/s-0029-1214161] [PMID: 20567731]
[136]
Takemura Y, Ishida H, Inoue Y. Utilization of common inflammatory markers in new, symptomatic, primary care outpatients based on their cost-effectiveness. Clin Chem Lab Med 2003; 41(5): 668-74.
[http://dx.doi.org/10.1515/CCLM.2003.101] [PMID: 12812265]
[137]
Osei-Bimpong A, Meek JH, Lewis SM. ESR or CRP? A comparison of their clinical utility. Hematology 2007; 12(4): 353-7.
[http://dx.doi.org/10.1080/10245330701340734] [PMID: 17654065]
[138]
Bottalico L, Tatullo M, Marrelli M, Santacroce L. Lights and shadows of dental implants: Focus on mucositis and perimplantitis and their biological markers. J Biol Regul Homeost Agents 2016; 30(3): 859-61.
[PMID: 27655511]
[139]
Di Serio F, Lovero R, D’Agostino D, et al. Evaluation of procalcitonin, Vitamin D and C-reactive protein levels in septic patients with positive emocultures. Our preliminary experience. Acta Med Mediter 2016; 32: 1911-4.

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