Abstract
Background: The association between KFD and autoimmune diseases, not only with systemic lupus erythematosus, has been repeatedly described.
Objective: The aim of this review is to evaluate whether an overlap syndrome is present between KFD and autoimmune diseases, whether there is a chronological and a casual relationship between the pathologies.
Methods: The databases used for the overlap case search were Medline and Embase from which we extrapolated the studies of interest. The search queries used were: Kikuchi-Fujimoto Syndrome and juvenile idiopathic arthritis or systemic lupus erythematosus or Systemic Sclerosis or Antiphospholipid Syndrome or Sjogren's Syndrome. All study types were considered (n = 103).
Results: Total number of included studies are 43. We have shown that there is an "overlap" syndrome between KFD and other autoimmune diseases. The chronology of disease onset was variable; autoimmune disease may be "preceding" (n = 11 cases) or "simultaneous" (n = 20 cases) or "post" (n = 8 cases). Kikuchi-Fujimoto Syndrome. Also, the autoimmune disease can present with a complete clinical picture or only with the presence of autoantibodies.
Conclusion: the different pathologies associated with KFD with different chronologies would suggest that there is an alteration of the immune system that allows the pathologies to occur in different temporal relationships.
Keywords: Kikuchi-fujimoto disease, juvenile idiopathic arthritis, systemic lupus erythematosus, systemic sclerosis, antiphospholipid syndrome, sjogren's syndrome, histiocytes.
[PMID: 28195263]
[http://dx.doi.org/10.1309/YF081L4TKYWVYVPQ] [PMID: 15272543]
[http://dx.doi.org/10.1016/S0194-5998(02)23291-X] [PMID: 12748557]
[http://dx.doi.org/10.1002/ccr3.3373] [PMID: 33363963]
[http://dx.doi.org/10.1080/08860220802595518] [PMID: 19212912]
[http://dx.doi.org/10.1186/s40064-015-0925-7] [PMID: 25897412]
[http://dx.doi.org/10.12659/AJCR.927351] [PMID: 33677464]
[http://dx.doi.org/10.1136/bcr-2020-240752]
[http://dx.doi.org/10.25259/IJDVL_893_18] [PMID: 33580926]
[http://dx.doi.org/10.1097/DAD.0000000000001764] [PMID: 32809980]
[http://dx.doi.org/10.1097/RHU.0000000000001287]
[http://dx.doi.org/10.5070/D3268049885]
[http://dx.doi.org/10.12890/2020_001516]
[http://dx.doi.org/10.1186/s13256-019-2100-1]
[http://dx.doi.org/10.1093/rheumatology/key353] [PMID: 30521051]
[http://dx.doi.org/10.29271/jcpsp.2018.06.S143] [PMID: 29866252]
[http://dx.doi.org/10.1007/s10792-017-0650-z] [PMID: 28695380]
[http://dx.doi.org/10.1046/j.1365-2559.1999.0669a.x] [PMID: 10231407]
[http://dx.doi.org/10.4321/S0212-71992001000800007] [PMID: 11589082]
[http://dx.doi.org/10.1097/MD.0000000000000220] [PMID: 25500707]
[PMID: 11326493]
[http://dx.doi.org/10.1007/s10067-004-0923-6] [PMID: 15517448]
[http://dx.doi.org/10.1007/s00296-004-0507-4] [PMID: 15645234]
[http://dx.doi.org/10.1097/MEG.0b013e32825a6a9e] [PMID: 18090996]
[http://dx.doi.org/10.1093/rheumatology/ken008] [PMID: 18304938]
[http://dx.doi.org/10.1016/j.revmed.2007.07.012] [PMID: 17981372]
[http://dx.doi.org/10.3109/s10165-009-0269-7] [PMID: 20082108]
[http://dx.doi.org/10.1016/j.jmv.2011.05.004] [PMID: 21757306]
[http://dx.doi.org/10.1016/j.semarthrit.2011.11.001]
[http://dx.doi.org/10.1097/RHU.0b013e3182a6a924] [PMID: 24048114]
[http://dx.doi.org/10.1016/j.ajoc.2016.06.004] [PMID: 29503907]
[http://dx.doi.org/10.1186/s13256-021-02949-5]
[http://dx.doi.org/10.1016/j.ajoc.2021.101041] [PMID: 33732946]
[http://dx.doi.org/10.1111/j.1346-8138.2003.tb00443.x] [PMID: 12928530]
[http://dx.doi.org/10.1007/s10067-005-0184-z] [PMID: 16465479]
[http://dx.doi.org/10.1177/1066896912467369] [PMID: 23204033]
[PMID: 26770297]
[http://dx.doi.org/10.12890/2018_000856] [PMID: 30756036]
[http://dx.doi.org/10.5114/reum.2020.98438] [PMID: 32921833]
[http://dx.doi.org/10.1007/s00431-013-2131-3] [PMID: 23955486]
[http://dx.doi.org/10.3109/03009742.2015.1033009] [PMID: 25974073]
[http://dx.doi.org/10.1093/rheumatology/keg167] [PMID: 12649409]
[http://dx.doi.org/10.1016/S0049-0172(96)80028-X] [PMID: 8870115]
[http://dx.doi.org/10.1177/0961203309345793] [PMID: 19933723]
[http://dx.doi.org/10.1007/s11420-009-9123-x] [PMID: 19609622]
[PMID: 6282130]
[http://dx.doi.org/10.1093/rheumatology/kei074] [PMID: 16352644]
[http://dx.doi.org/10.3345/kjp.2012.55.11.445] [PMID: 23227065]
[http://dx.doi.org/10.1016/j.humpath.2012.05.016] [PMID: 22939574]
[http://dx.doi.org/10.1007/s10067-006-0230-5] [PMID: 16538388]