A Review on Edible Vaccines and Biopharmaceutical Products from Plants

Title:A Review on Edible Vaccines and Biopharmaceutical Products from Plants

Volume: 24 Issue: 4

Author(s): Pankaj Kumar Paradia, Rameshwar Bhavale, Tejas Agnihotri and Aakanchha Jain*

Affiliation:

• Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A), An Institute of National Importance, Government of India, Gujrat, India

Keywords: Biopharmaceutical, edible vaccine, glycosylation, mass vaccination, plantibodies, transgenic plant.

Abstract: Plants have substantial potential for the development of various biopharmaceuticals. Plants provide a cost-effective and direct source for the production of biopharmaceuticals such as vaccines, antibodies, proteins, enzymes, and hormones. In most cases, purification is an important and expensive step in the production of these substances. The problem can be resolved when it is produced in plants and the whole plant can be consumed. Direct ingestion of plant materials may help in overcoming the purification step. Being produced in seeds, fruits and tubers, it helps in providing more immunization in developing countries at a cheaper rate. Moreover, it can be administered more efficiently than any other dosage forms. This review focuses on various immunization and therapeutic products that are produced in plants along with currently available formulations in each category.

Cite this article as:

Paradia Kumar Pankaj, Bhavale Rameshwar, Agnihotri Tejas and Jain Aakanchha*, A Review on Edible Vaccines and Biopharmaceutical Products from Plants, Current Pharmaceutical Biotechnology 2023; 24(4) . https://dx.doi.org/10.2174/1389201023666220803151039