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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Biography

Meet the Editorial Board Member

Author(s): María Luz López Rodríguez

Volume 29, Issue 28, 2022

Published on: 29 June, 2022

Page: [4777 - 4778] Pages: 2

DOI: 10.2174/092986732928220629150657

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[1]
Jimenez-Blasco, D.; Busquets-Garcia, A.; Hebert-Chatelain, E.; Serrat, R.; Vicente-Gutierrez, C.; Ioannidou, C.; Gómez-Sotres, P.; Lopez-Fabuel, I.; Resch-Beusher, M.; Resel, E.; Arnouil, D.; Saraswat, D.; Varilh, M.; Cannich, A.; Julio-Kalajzic, F.; Bonilla-Del Río, I.; Almeida, A.; Puente, N.; Achicallende, S.; López-Rodríguez, M.L.; Jollé, C.; Déglon, N.; Pellerin, L.; Josephine, C.; Bonvento, G.; Panatier, A.; Lutz, B.; Piazza, P.V.; Guzmán, M.; Bellocchio, L.; Bouzier-Sore, A-K.; Grandes, P.; Bolaños, J.P.; Marsicano, G. Glucose metabolism links astroglial mitochondria to cannabinoid effects. Nature, 2020, 583(7817), 603-608.
[http://dx.doi.org/10.1038/s41586-020-2470-y] [PMID: 32641832]
[2]
Medina, R.A.; Vázquez-Villa, H.; Gómez-Tamayo, J.C.; Benhamú, B.; Martín-Fontecha, M.; de la Fuente, T.; Caltabiano, G.; Hedlund, P.B.; Pardo, L.; López-Rodríguez, M.L. The extracellular entrance provides selectivity to serotonin 5-HT7 receptor antagonists with antidepressant-like behavior in vivo. J. Med. Chem., 2014, 57(15), 6879-6884.
[http://dx.doi.org/10.1021/jm500880c] [PMID: 25073094]
[3]
Gamo, A.M.; González-Vera, J.A.; Rueda-Zubiaurre, A.; Alonso, D.; Vázquez-Villa, H.; Martín-Couce, L.; Palomares, Ó.; López, J.A.; Martín-Fontecha, M.; Benhamú, B.; López-Rodríguez, M.L.; Ortega-Gutiérrez, S. Chemoproteomic approach to explore the target profile of gpcr ligands: application to 5-HT1A and 5-HT6 receptors. Chemistry, 2016, 22(4), 1313-1321.
[http://dx.doi.org/10.1002/chem.201503101] [PMID: 26560738]
[4]
Marín-Ramos, N.I.; Piñar, C.; Vázquez-Villa, H.; Martín-Fontecha, M.; González, Á.; Canales, Á.; Algar, S.; Mayo, P.P.; Jiménez-Barbero, J.; Gajate, C.; Mollinedo, F.; Pardo, L.; Ortega-Gutiérrez, S.; Viso, A.; López-Rodríguez, M.L. Development of a nucleotide exchange inhibitor that impairs ras oncogenic signaling. Chemistry, 2017, 23(7), 1676-1685.
[http://dx.doi.org/10.1002/chem.201604905] [PMID: 27885731]
[5]
Wagner, R.; Stübiger, G.; Veigel, D.; Wuczkowski, M.; Lanzerstorfer, P.; Weghuber, J.; Karteris, E.; Nowikovsky, K.; Wilfinger-Lutz, N.; Singer, C.F.; Colomer, R.; Benhamú, B.; López-Rodríguez, M.L.; Valent, P.; Grunt, T.W. Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells. Oncotarget, 2017, 8(7), 11600-11613.
[http://dx.doi.org/10.18632/oncotarget.14591] [PMID: 28086243]
[6]
Gil-Ordóñez, A.; Martín-Fontecha, M.; Ortega-Gutiérrez, S.; López-Rodríguez, M.L. Monoacylglycerol lipase (MAGL) as a promising therapeutic target. Biochem. Pharmacol., 2018, 157, 18-32.
[http://dx.doi.org/10.1016/j.bcp.2018.07.036] [PMID: 30059673]
[7]
Marín-Ramos, N.I.; Balabasquer, M.; Ortega-Nogales, F.J.; Torrecillas, I.R.; Gil-Ordóñez, A.; Marcos-Ramiro, B.; Aguilar-Garrido, P.; Cushman, I.; Romero, A.; Medrano, F.J.; Gajate, C.; Mollinedo, F.; Philips, M.R.; Campillo, M.; Gallardo, M.; Martín-Fontecha, M.; López-Rodríguez, M.L.; Ortega-Gutiérrez, S. A potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor improves survival in ras-driven acute myeloid leukemia. J. Med. Chem., 2019, 62(13), 6035-6046.
[http://dx.doi.org/10.1021/acs.jmedchem.9b00145] [PMID: 31181882]
[8]
González-Gil, I.; Zian, D.; Vázquez-Villa, H.; Hernández-Torres, G.; Martínez, R.F.; Khiar-Fernández, N.; Rivera, R.; Kihara, Y.; Devesa, I.; Mathivanan, S.; Del Valle, C.R.; Zambrana-Infantes, E.; Puigdomenech, M.; Cincilla, G.; Sanchez-Martinez, M.; Rodríguez de Fonseca, F.; Ferrer-Montiel, A.V.; Chun, J.; López-Vales, R.; López-Rodríguez, M.L.; Ortega-Gutiérrez, S. A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration. J. Med. Chem., 2020, 63(5), 2372-2390.
[http://dx.doi.org/10.1021/acs.jmedchem.9b01287] [PMID: 31790581]

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