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Current Pharmaceutical Biotechnology

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ISSN (Print): 1389-2010
ISSN (Online): 1873-4316

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Mini-Review Article

Medicinal Plants with Anti-dengue and Immunomodulatory Activity

Author(s): Bandt-Pulido Juan-Pablo, Pedroza-Escobar David*, Salas-Rojas Mónica, Sharma Ashutosh, Nuñez-Avellaneda Daniel, Delgadillo-Guzmán Dealmy, García-Garza Rubén, Velázquez-Gauna Sergio-Everardo, Ramirez-Moreno Agustina, Vega-Menchaca María-Del-Carmen, Hernández-Herrera Alejandro-David and Castillo-Maldonado Irais*

Volume 24, Issue 4, 2023

Published on: 14 September, 2022

Page: [486 - 494] Pages: 9

DOI: 10.2174/1389201023666220520110204

Price: $65

Abstract

Dengue fever is a disease with a high mortality rate around the world, which is an important issue for the health authorities of many countries. As a result of this, the search for new drugs that are effective to combat this disease has become necessary. Medicinal plants have been used since ancient times to treat a wide list of diseases, including dengue fever. In this mini-review, 12 medicinal plants with known pharmacological properties are presented, which have been used in studies to evaluate their antiviral activity in vitro tests. Among the chemical agents involved in the antiviral response, found in the alcoholic extracts of these plants, are flavonoids, terpenes and alkaloids, which within the mechanism of action in blocking viral replication are considered entry inhibitors, fusion inhibitors, translation inhibitors and protease inhibitors. The present work shows whether these plants possess antiviral activity and the chemical compounds involved in this response.

Keywords: Dengue virus, antiviral activities, immunomodulatory activity, medicine plants, RNA, population.

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