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Mini-Reviews in Organic Chemistry


ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

Biosynthetic Pathways for Rebeccamycin Family of Natural Products

Author(s): M. Mujahid Alam, Ravi Varala*, Chandra Mohan Kurmarayuni, Hari Babu Bollikolla and Narsimhaswamy Dubasi

Volume 20, Issue 3, 2023

Published on: 10 August, 2022

Page: [309 - 321] Pages: 13

DOI: 10.2174/1570193X19666220429120600

Price: $65


The isolation of Rebeccamycin, a family of indolocarbazole alkaloids from natural sources, and the biosynthesis of this class of compounds are briefly reviewed. Rebeccamycin and its analogues have been extensively studied by medicinal chemists, over the last four decades, due to its wide range of biological activities, predominantly with neuroprotective and antitumor properties.

Keywords: Indolocarbazoles, Rebeccamycin, antitumor, neuroprotective, biosynthesis, isolation.

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