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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Bioactive Compounds and Diabetes Mellitus: Prospects and Future Challenges

Author(s): Md. Mominur Rahman, Md. Rezaul Islam, Fazle Rabbi, Mohammad Touhidul Islam, Sharifa Sultana, Muniruddin Ahmed, Aayush Sehgal, Sukhbir Singh, Neelam Sharma and Tapan Behl*

Volume 28, Issue 16, 2022

Published on: 25 May, 2022

Page: [1304 - 1320] Pages: 17

DOI: 10.2174/1381612828666220412090808

Price: $65


Diabetes mellitus is a metabolic condition that influences the endocrine framework. Hyperglycemia and hyperlipidemia are two of the most widely recognized metabolic irregularities in diabetes and two of the most well-known reasons for diabetic intricacies. Diabetes mellitus is a persistent illness brought about by metabolic irregularities in hyperglycemic pancreatic cells. Hyperglycemia can be brought about by an absence of insulin-producing beta cells in the pancreas (Type 1 diabetes mellitus) or inadequate insulin creation that does not work effectively (Type 2 diabetes mellitus). Present diabetes medication directs blood glucose levels in the systemic circulation to the typical levels. Numerous advanced prescription medicines have many negative results that can bring about unexpected severe issues during treatment of the bioactive compound from a different source that is beneficially affected by controlling and adjusting metabolic pathways or cycles. Moreover, a few new bioactive medications disengaged from plants have shown antidiabetic action with more noteworthy adequacy than the oral hypoglycemic agent that specialists have utilized in clinical treatment lately. Since bioactive mixtures are collected from familiar sources, they have a great activity in controlling diabetes mellitus. This study discusses bioactive compounds, their activity in managing diabetes mellitus, and their prospects. Though bioactive compounds have many health-beneficial properties, adequate clinical studies still need to acknowledge that they effectively manage diabetes mellitus.

Keywords: Diabetes mellitus, bioactive compounds, hyperglycemia, hyperlipidemia, insulin, medications.

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