Login Register Cart 0
Generic placeholder image

Infectious Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Editorial

SARS-CoV-2-Induced Neurological Disorders in Symptomatic Covid-19 and Long Covid Patients: Key Role of Brain Renin-Angiotensin System

Author(s): Ziad Fajloun*, Hervé Kovacic, Cédric Annweiler, Yingliang Wu, Zhijian Cao and Jean-Marc Sabatier*

Volume 22, Issue 5, 2022

Published on: 22 April, 2022

Article ID: e060422203203 Pages: 3

DOI: 10.2174/1871526522666220406124618

[1]
Hofer U. Dose-dependent COVID-19 symptoms. Nat Rev Microbiol 2021; 19(11): 682.
[http://dx.doi.org/10.1038/s41579-021-00634-4] [PMID: 34493851]
[2]
Mandal S, Barnett J, Brill SE, et al. ‘Long-COVID’: a cross-sectional study of persisting symptoms, biomarker and imaging abnormalities following hospitalisation for COVID-19. Thorax 2021; 76(4): 396-8.
[http://dx.doi.org/10.1136/thoraxjnl-2020-215818] [PMID: 33172844]
[3]
NICE defines 'long Covid' as symptoms lasting more than 12 weeks. GEMMA MITCHELL, 30 October, 2020. Available from: https://www.nursingtimes.net/news/coronavirus/nice-defines-long-covid-as-symptoms-lasting-more-than-12-weeks-30-10-2020/
[4]
Kang H, Wang Y, Tong Z, Liu X. Retest positive for SARS-CoV-2 RNA of “recovered” patients with COVID-19: Persistence, sampling issues, or re-infection? J Med Virol 2020; 92(11): 2263-5.
[http://dx.doi.org/10.1002/jmv.26114] [PMID: 32492212]
[5]
Naendrup JH, Garcia Borrega J, Eichenauer DA, Shimabukuro-Vornhagen A, Kochanek M, Böll B. Reactivation of EBV and CMV in severe COVID-19-epiphenomena or trigger of hyperinflammation in need of treatment? A large case series of critically ill patients. J Intensive Care Med 2021; 18: 8850666211053990.
[http://dx.doi.org/10.1177/08850666211053990] [PMID: 34791940]
[6]
Sacchi MC, Tamiazzo S, Stobbione P, et al. SARS-CoV-2 infection as a trigger of autoimmune response. Clin Transl Sci 2021; 14(3): 898-907.
[http://dx.doi.org/10.1111/cts.12953] [PMID: 33306235]
[7]
Amiral J, Vissac AM, Seghatchian J. Covid-19, induced activation of hemostasis, and immune reactions: Can an auto-immune reaction con-tribute to the delayed severe complications observed in some patients? Transfus Apheresis Sci 2020; 59(3): 102804.
[http://dx.doi.org/10.1016/j.transci.2020.102804] [PMID: 32387238]
[8]
Lee DH, Heidecke H, Schröder A, et al. Increase of angiotensin II type 1 receptor auto-antibodies in Huntington’s disease. Mol Neurodegener 2014; 9: 49.
[http://dx.doi.org/10.1186/1750-1326-9-49] [PMID: 25398321]
[9]
Burks SM, Rosas-Hernandez H, Alejandro Ramirez-Lee M, Cuevas E, Talpos JC. Can SARS-CoV-2 infect the central nervous system via the olfactory bulb or the blood-brain barrier? Brain Behav Immun 2021; 95: 7-14.
[http://dx.doi.org/10.1016/j.bbi.2020.12.031] [PMID: 33412255]
[10]
Guedj E, Campion JY, Dudouet P, et al. 18F-FDG brain PET hypometabolism in patients with long COVID. Eur J Nucl Med Mol Imaging 2021; 48(9): 2823-33.
[http://dx.doi.org/10.1007/s00259-021-05215-4] [PMID: 33501506]
[11]
Douaud G, Lee S, Alfaro-Almagro F, et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 2022; 2.
[http://dx.doi.org/10.1038/s41586-022-04569-5] [PMID: 35255491]
[12]
El-Arif G, Farhat A, Khazaal S, et al. The renin-angiotensin system: A key role in SARS-CoV-2-induced COVID-19. Molecules 2021; 26(22): 6945.
[http://dx.doi.org/10.3390/molecules26226945] [PMID: 34834033]
[13]
Annweiler C, Cao Z, Wu Y, et al. Counter-regulatory ‘renin-angiotensin’ system-based candidate drugs to treat COVID-19 diseases in SARS-CoV-2-infected patients. Infect Disord Drug Targets 2020; 20(4): 407-8.
[http://dx.doi.org/10.2174/1871526520666200518073329] [PMID: 32418532]
[14]
Cosarderelioglu C, Nidadavolu L, George C. Brain renin-angiotensin system at the intersect of physical and cognitive frailty. Front Neurosci 2020; 14: 586314.
[http://dx.doi.org/10.3389/fnins.2020.586314] [PMID: 33117127]
[15]
Annweiler C, Bourgeais A, Faucon E, Cao Z, Wu Y, Sabatier JM. Neurological, cognitive and behavioral disorders during COVID-19: The nitric oxide track. J Am Geriatr Soc 2020; 68(9): 1922-3.
[http://dx.doi.org/10.1111/jgs.16671] [PMID: 32583434]
[16]
SeyedAlinaghi S, Mehrtak M, MohsseniPour M, et al. Genetic susceptibility of COVID-19: A systematic review of current evidence. Eur J Med Res 2021; 26(1): 46.
[http://dx.doi.org/10.1186/s40001-021-00516-8] [PMID: 34016183]
[17]
Annweiler C, Cao Z, Papon N, Kovacic H, Sabatier JM. Counter-regulatory renin-angiotensin system: An important line of research to un-derstand and limit the severity of COVID-19. Infect Disord Drug Targets 2021. Epub ahead of print
[http://dx.doi.org/10.2174/1871526521666210910063227] [PMID: 34515015]
[18]
Annweiler C, Cao Z, Sabatier JM. Point of view: Should COVID-19 patients be supplemented with vitamin D? Maturitas 2020; 140: 24-6.
[http://dx.doi.org/10.1016/j.maturitas.2020.06.003] [PMID: 32972631]
[19]
Annweiler C, Hanotte B, Grandin de l’Eprevier C, Sabatier JM, Lafaie L, Célarier T. Vitamin D and survival in COVID-19 patients: A quasi-experimental study. J Steroid Biochem Mol Biol 2020; 204: 105771.
[http://dx.doi.org/10.1016/j.jsbmb.2020.105771] [PMID: 33065275]
[20]
Cao Z, Wu Y, Faucon E, Sabatier JM. SARS-CoV-2 & Covid-19: Key-roles of the renin-angiotensin system/Vitamin D impacting drug and vaccine developments. Infect Disord Drug Targets 2020; 20(3): 348-9.
[http://dx.doi.org/10.2174/1871526520999200505174704] [PMID: 32370727]

Rights & Permissions Print Cite
Article Metrics
34
1
© 2024 Bentham Science Publishers | Privacy Policy