Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications

Title: Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications

Volume: 12 Issue: 10

Author(s): G. Lena and G. Guichard

Affiliation:

• CNRS, Institut de Biologie Moleculaire et Cellulaire, Laboratoire d'Immunologie et Chimie Therapeutiques, 15 rue Rene Descartes, 67000 Strasbourg, France.,France

Abstract: Compounds with triazepine skeletons have attracted much attention as a result of their interesting biological properties. Triazepandiones represent a particular subset that includes sixteen possible functional isomers, of which nine have been reported in the literature and patents. A survey of the literature indicates that intramolecular cyclization reactions and transformation of other heterocyclic systems are the two main synthetic approaches employed to prepare triazepandiones. This review covers both synthetic methods and applications of compounds with triazepandione skeletons.

Cite this article as:

Lena G. and Guichard G., Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications, Current Organic Chemistry 2008; 12(10) . https://dx.doi.org/10.2174/138527208784911879