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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Synthetic Methods for the Preparation of Triazepandiones and Review of their Applications

Author(s): G. Lena and G. Guichard

Volume 12, Issue 10, 2008

Page: [813 - 835] Pages: 23

DOI: 10.2174/138527208784911879

Price: $65


Compounds with triazepine skeletons have attracted much attention as a result of their interesting biological properties. Triazepandiones represent a particular subset that includes sixteen possible functional isomers, of which nine have been reported in the literature and patents. A survey of the literature indicates that intramolecular cyclization reactions and transformation of other heterocyclic systems are the two main synthetic approaches employed to prepare triazepandiones. This review covers both synthetic methods and applications of compounds with triazepandione skeletons.

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