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Current Traditional Medicine

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ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

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Review Article

The Potential Impact of Ayurvedic Traditional Bhasma on SARS-CoV- 2- Induced Pathogenesis

Author(s): Pankaj Kumar*, Remya Jayakumar, Manoj Kumar Dash and Namrata Joshi

Volume 9, Issue 3, 2023

Published on: 30 August, 2022

Article ID: e210322202483 Pages: 16

DOI: 10.2174/2215083808666220321145803

Price: $65

Abstract

The mass casualties caused by the delta variant and the wave of the newer “Omicron” variant of SARS-COV-2 in India have brought about great concern among healthcare officials. The government and healthcare agencies are seeking effective strategies to counter the pandemic. The application of nanotechnology and repurposing of drugs are reported as promising approaches in the management of COVID-19 disease. It has also immensely boomed the search for productive, reliable, cost-effective, and bio-assimilable alternative solutions. Since ancient times, the traditionally employed Ayurvedic bhasmas have been used for diverse infectious diseases, which are now employed as nanomedicine that could be applied for managing COVID-19-related health anomalies. Like currently engineered metal nanoparticles (NPs), the bhasma nanoparticles (BNPs) are also packed with unique physicochemical properties, including multi-elemental nanocrystalline composition, size, shape, dissolution, surface charge, hydrophobicity, and multi-pathway regulatory as well as modulatory effects. Because of these conformational and configurational-based physicochemical advantages, Bhasma NPs may have promising potential to manage the COVID-19 pandemic and reduce the incidence of pneumonia-like common lung infections in children as well as age-related inflammatory diseases via immunomodulatory, anti-inflammatory, antiviral, and adjuvant- related properties.

Keywords: Bhasma, marana, transition metal, nanocrystalline structure, proinflammatory, nanoparticles, gut microbiome.

Graphical Abstract

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