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Recent Patents on Nanotechnology


ISSN (Print): 1872-2105
ISSN (Online): 2212-4020

Review Article

Review on Different Vesicular Drug Delivery Systems (VDDSs) and Their Applications

Author(s): Asma M. Alenzi, Sana A. Albalawi, Shatha G. Alghamdi, Rawan F. Albalawi, Hadeel S. Albalawi and Mona Qushawy*

Volume 17, Issue 1, 2023

Published on: 22 April, 2022

Page: [18 - 32] Pages: 15

DOI: 10.2174/1872210516666220228150624

Price: $65


Background: Colloidal dispersions, also known as vesicular drug delivery systems (VDDSs), are highly ordered assemblies composed of one or more concentric bilayers formed by the self-assembly of amphiphilic building blocks in the presence of water.

Objective: VDDSs are important to target the entrapped drugs at specific sites inside the body, control the drug release, enhance the drug bioavailability, and reduce undesired side effects.

Methods: There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic drugs. According to the patent composition, VDDSs are classified into lipid-based and nonlipid- based VDDSs.

Results: There are different types of VDDSs which include liposomes, ethosomes, transferosomes, ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc.

Conclusion: This review article aims to address the different types of VDDSs, their advantages and disadvantages, and their therapeutic applications.

Keywords: Drug delivery, niosomes, liposomes, bioavailability, drug targeting, colloidal dispersion.

Graphical Abstract
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