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Review Article

Diagnostic Approach and Treatment Regimens in Adult Patients Suffering from Antibody- mediated or Paraneoplastic Encephalitis

Author(s): Stefan Macher*, Gabriel Bsteh, Thomas Berger and Romana Höftberger

Volume 28, Issue 6, 2022

Published on: 31 January, 2022

Page: [454 - 467] Pages: 14

DOI: 10.2174/1381612828666220131093259

Price: $65

Abstract

Identification of patients with antibody-mediated encephalitis poses a diagnostic challenge, and any delay in that aspect will increase the interval until the initiation of immunotherapy and may negatively affect the patient´s clinical outcome. Within this review, we focus on therapeutic strategies in antibody-mediated encephalitis and propose how to proceed with patients who are suspected of having encephalitis of unknown origin. We further briefly outline differences in the treatment of paraneoplastic and antibody-mediated encephalitis according to its pathomechanisms.

Keywords: Antibody-mediated encephalitis, paraneoplastic encephalitis, auto-antibodies, treatment, regimens, immunotherapy.

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