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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Recent Advances in Utilization of Deep Eutectic Solvents: An Environmentally Friendly Pathway for Multi-component Synthesis

Author(s): Ajay Thakur*, Monika Verma, Ruchi Bharti* and Renu Sharma

Volume 26, Issue 3, 2022

Published on: 15 February, 2022

Page: [299 - 323] Pages: 25

DOI: 10.2174/1385272826666220126165925

Price: $65


With the increasing analysis of saving the environment, the researchers demonstrated much effort to replace toxic chemicals with environmentally benign ones. Eutectic mixtures are those solvents that fulfill the criteria of green solvents. The synthesis of organic compounds in the chemical and pharmaceutical industries makes it necessary to find unconventional solvents that cause no harmful impact on health parameters. This review showed that using deep eutectic mixture-based solvents to overcome the hazardous effects of harmful volatile organic solvents over the past few years has gained much more appeal. In most applications, deep eutectic mixtures are used for a solvent or co-solvent role, as they are easy to use, easy dissolution of reactants, and non-evaporative nature. However, deep eutectic mixtures have also been investigated as catalysts, and this dual functionality has much scope in the future, as a significantly less range of deep eutectic mixtures is utilized for this.

Keywords: Deep eutectic mixtures, green solvent, multicomponent reaction, heterocycles, biorenewable, biotransformation.

Graphical Abstract
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