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Current Neurovascular Research


ISSN (Print): 1567-2026
ISSN (Online): 1875-5739

Research Article

Nonfocal Symptoms in Patients with Transient Ischemic Attack and Association with Stroke Risk

Author(s): Shuxiang Yang, Lu Zhao*, Lulu Pei, Shuang Cao, Yuan Gao, Hui Fang, Kai Liu, Shilei Sun, Jun Wu, Bo Song and Yuming Xu

Volume 18, Issue 5, 2021

Published on: 31 December, 2021

Page: [474 - 478] Pages: 5

DOI: 10.2174/1567202619666211217124919

Price: $65


Background and Objective: Patients with transient ischemic attack(TIA)occasionally showed nonfocal symptoms, such as decreased consciousness, amnesia and non-rotatory dizziness. This study intended to evaluate the effect of nonfocal symptoms on the prognosis of patients with TIA.

Methods: Data from the prospective hospital-based TIA database of the First Affiliated Hospital of Zhengzhou University were analyzed. The predictive outcome was stroke occurrence at 1 year. Cumulative risks of stroke in patients with and without nonfocal symptoms were estimated with Kaplan-Meier models.

Results: We studied 1384 patients with TIA (842 men; mean age, 56±13 years), including 450 (32.5%) with nonfocal symptoms. In the first year after TIA, stroke occurred in 168(12.1%) patients. There was no difference in the risk of stroke between patients with both focal and nonfocal symptoms and patients with focal symptoms alone (11.8% vs 12.4%, log-rank; P=0.691).

Conclusions: The occurrence of nonfocal symptoms did not increase the risk of stroke at one-year follow-up compared to the occurrence of focal symptoms alone.

Keywords: Transient ischemic attack, nonfocal symptoms, stroke, prognosis, diffusion-weighted imaging

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