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Current Pharmaceutical Design


ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

General Review Article

H19: A Vital Long Noncoding RNA in the Treatment of Diabetes and Diabetic Complications

Author(s): Leiqi Zhu, Yuanyang Li, Fangqi Xia, Mengzhen Xue, Yaqi Wang, Dengke Jia, Yan Gao, Luoying Li, Yue Shi, Silong Chen, Guangfu Xu and Chengfu Yuan*

Volume 28, Issue 12, 2022

Published on: 12 January, 2022

Page: [1011 - 1018] Pages: 8

DOI: 10.2174/1381612827666211210123959

Price: $65


Background: Increasing academic efforts have been made to explore the correlation of long noncoding RNAs (lncRNAs) with human diseases, particularly metabolic diseases like diabetes mellitus. Taking lncRNA H19 as an example, this review intends to reveal the functions and mechanism of lncRNA H19 in diabetes mellitus and diabetic complications.

Methods: The research results associated with lncRNA H19 and diabetes mellitus are collected and summarized on PubMed.

Conclusion: LncRNA H19 is a potential instructive marker for the treatment of diabetes mellitus and diabetic complications.

Keywords: H19, long noncoding RNA, miRNA, treatment, hyperglycemia, diabetes, diabetic complications.

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