Generic placeholder image

Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Recent Advances on Synthesis of 1,4-Benzoxazines and its Derivatives

Author(s): Wei Liang, Li-Jing Min, Liang Han and Xing-Hai Liu*

Volume 25 , Issue 23 , 2021

Published on: 27 November, 2021

Page: [2840 - 2855] Pages: 16

DOI: 10.2174/1385272825666211117154031

Price: $65

Abstract

1,4-benzoxazine compounds are an important class of heterocyclic compounds. Ever since 1,4-benzoxazine was discovered in 1959, it has attracted chemists due to its unique physiological activities, and their synthesis and application have been studied. However, the traditional synthesis methods of 1,4-benzoxazines have some drawbacks, such as complicated steps, harsh reaction conditions and low yield. Therefore, it is still a significant direction to develop new and efficient synthesis methods. In this paper, the synthesis methods and reaction mechanisms of these compounds are reviewed, and the application prospect of 1,4- benzoxazine and its derivatives as a dominant active structure in the future is discussed.

Keywords: 1, 4-benzoxazines, derivatives, heterocyclic compounds, application, synthesis methods, reaction mechanisms.

Graphical Abstract

Rights & Permissions Print Export Cite as
© 2022 Bentham Science Publishers | Privacy Policy