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Current Organic Synthesis


ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

General Review Article

Recent Advances in the Green Synthesis of Heterocycles: From Building Blocks to Biologically Active Compounds

Author(s): Christian Schäfer, Hyejin Cho, Bernadett Vlocskó, Guoshu Xie and Béla Török*

Volume 19, Issue 3, 2022

Published on: 10 December, 2021

Page: [426 - 462] Pages: 37

DOI: 10.2174/1570179418666210910110205


Recent advances in the environmentally benign synthesis of common heterocycles are described. This account features three main parts; the preparation of non-aromatic heterocycles, one-ring aromatic heterocycles and their condensed analogs. Due to the great variety of and high interest in these compounds, this work focuses on providing representative examples of the preparation of the target compounds.

Keywords: Sustainable synthesis, non-aromatic heterocycles, aromatic heterocycles, condensed heterocycles, epoxides, aziridines, azetidines, pyrroles, indoles, quinolines, pyridines, pyrimidines, condensed heterocycles.

Graphical Abstract
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