The Role of Coronary Physiology in Contemporary Percutaneous Coronary
Interventions

Federico       Marin; Roberto       Scarsini; Dimitrios       Terentes-Printzios; Rafail    A.    Kotronias; Flavio       Ribichini; Adrian    P.    Banning; Giovanni    Luigi    De Maria
Abstract

Invasive assessment of coronary physiology has radically changed the paradigm of myocardial revascularization in patients with coronary artery disease. Despite the prognostic improvement associated with ischemia-driven revascularization strategy, functional assessment of angiographic intermediate epicardial stenosis remains largely underused in clinical practice. Multiple tools have been developed or are under development in order to reduce the invasiveness, cost, and extra procedural time associated with the invasive assessment of coronary physiology. Besides epicardial stenosis, a growing body of evidence highlights the role of coronary microcirculation in regulating coronary flow with consequent pathophysiological and clinical and prognostic implications. Adequate assessment of coronary microcirculation function and integrity has then become another component of the decision-making algorithm for optimal diagnosis and treatment of coronary syndromes.
This review aims at providing a comprehensive description of tools and techniques currently available in the catheterization laboratory to obtain a thorough and complete functional assessment of the entire coronary tree (both for the epicardial and microvascular compartments).
Keywords: Coronary physiology, myocardial revascularization, functional assessment, percutaneous coronary intervention, ischemic heart disease, microvascular dysfunction.
Graphical Abstract

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DOI https://dx.doi.org/10.2174/1573403X17666210908114154	Print ISSN 1573-403X
Publisher Name Bentham Science Publisher	Online ISSN 1875-6557
Current Cardiology Reviews

The Role of Coronary Physiology in Contemporary Percutaneous Coronary Interventions

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