Abstract
Background: The polyphenols from red fruits exhibit protective effects against degenerative diseases, such as diabetes mellitus type 2, cardiovascular disease and others.
Objective: In this small pilot intervention study with only ten volunteers, we investigated the influence of phenolic extracts prepared from an aronia juice, and a red grape juice concentrate on peripheral glucose, blood glucose, and insulin after the intake of a drink containing these extracts plus maltodextrin and water.
Method: Maltodextrin in water served as control; additionally, phenolic extracts from aronia or grape juice were added. Blood samples were taken before ingestion of the bolus drink, and 30, 60, 90, 120, 180, 240, and 360 min after. Additionally, the peripheral glucose was measured continuously using a commercially available sensor system.
Results: In all ten volunteers, the intake of aronia extract (100 mg) reduced both, the peripheral glucose and the blood glucose levels significantly (p≤0.05) in comparison to the control. Blood insulin levels were not affected. Whereas the intake of red grape extract (120 mg) did not reduce the glucose levels, but increased the insulin levels significantly.
Conclusion: Our pilot study showed that even low amounts of a phenolic aronia extract could lower the glucose absorption. Thus, due to the blood glucose lowering effects of aronia phenolics in healthy volunteers, these preliminary results warrant further investigation in the frame of a follow- up study with larger number of volunteers.
Keywords: Blood glucose, peripheral glucose, human intervention study, aronia, red grape, polyphenolic extracts.
Graphical Abstract
Call for Papers in Thematic Issues
Functional Food Factors and Therapeutics
The development of new rugs in disease therapy is focused on targeting molecules involved in the growth and death of cells in attracting attention to immunotherapy. In the control and treatment of disease, classical drugs, which have been used for a long time, are still widely used as primary selective ...read more
Treatment of chronic diseases with edible Natural Products. The case of cardiovascular agents"
The aim of this special issue is to highlight the importance of the use of edible natural products (both isolated pure compounds and extracts-mixtures) in the treatment of cardiovascular diseases. In this topic, it would be interesting to include all the potential researchers that have been involved in the study ...read more
Related Books
Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention
Green Extraction Techniques in Food Analysis
Algal Functional Foods and Nutraceuticals: Benefits, Opportunities, and Challenges
Micronutrients: The Key to Good Health
Capillary Electrophoresis in Food Analysis
Nutritional Biochemistry: From the Classroom to the Research Bench
Hypersensitivity to Vitamins
Foods for Special Dietary Regimens
15