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Current Psychopharmacology


ISSN (Print): 2211-5560
ISSN (Online): 2211-5579

Case Report

Captagon Use in a Patient with Iatrogenic Opioid Use Disorder

Author(s): Mohammed Hamdan, Samer El Hayek and Maya Bizri*

Volume 10, Issue 3, 2021

Published on: 01 July, 2021

Page: [240 - 243] Pages: 4

DOI: 10.2174/2211556010666210701163649

Price: $65


Background: Captagon or Fenethylline is a synthetic theophylline derivative of amphetamine that is widely available for recreational use in the Middle East. It has pain-reducing properties and is known to induce restlessness, irritability, and psychotic symptoms.

Case Presentation: A middle-aged man with iatrogenic opioid use disorder was admitted for acute cholecystitis. A week following cholecystectomy, the patient used Captagon while hospitalized to manage opioid withdrawal pain. He experienced waxing and waning episodes of irritability, aggressiveness, disorganized behaviors, delusions, and hallucinations, all concurrent with his Captagon intake. These episodes were managed similarly to intoxication with other stimulant types.

Conclusion: Careful patient counseling and close follow-up are essential when opioids are prescribed. Captagon’s pain-reducing properties make it an attractive and dangerous option for Middle Eastern patients suffering from opioid withdrawal. Captagon intoxication is currently managed similarly to other stimulant types, but more studies are needed to develop management guidelines specific to this substance.

Keywords: Captagon, acute intoxication, opioid withdrawal, consultation-liaison psychiatry, iatrogenic opioid, theophylline derivative.

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