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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

Review Article

Eugenol as a Potential Drug Candidate: A Review

Author(s): Mohamad Taleuzzaman, Pooja Jain, Rishabh Verma, Zeenat Iqbal* and Mohd. Aamir Mirza*

Volume 21 , Issue 20 , 2021

Published on: 01 July, 2021

Page: [1804 - 1815] Pages: 12

DOI: 10.2174/1568026621666210701141433

Price: $65

Abstract

Eugenol is a bioactive compound widely available in many herbs like clove, cinnamon, tulsi, pepper etc. The compound is known for its antioxidant, antimicrobial, anesthetic, anti-inflammatory, neuroprotective, anti-diabetic, and anti-cancer activities. In pharmaceutical analysis, eugenol is used as a marker for single drugs and drug products. Dental care, household, and personal hygiene products are other areas where it has established its potential. In the food industry, eugenol is used as a flavouring agent in non-alcoholic beverages, baked foods, and chewing gums.

Considering the huge potential of eugenol, this review is an attempt to collate the regulatory information, physico-chemical properties, toxicity profile, marketed conventional and novel formulations, analytical methods, extraction procedures, recent patents and clinical trials of the moiety. Based on literature survey a schematic diagram of mechanism of action has also been made.

Keywords: Pharmacological properties, Pharmacokinetics, Analytical techniques, Clinical trials, Patents, Eugenol.

Graphical Abstract

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