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Current Organic Chemistry


ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Tin-mediated Radical Cyclization Reactions

Author(s): Saima malik*, Aditya G. Lavekar and Bimal Krishna Banik*

Volume 25, Issue 22, 2021

Published on: 17 June, 2021

Page: [2708 - 2739] Pages: 32

DOI: 10.2174/1385272825666210617165918

Price: $65


Radical chemistry is known for two centuries. Due to the fascinating nature of the radical-mediated processes, these reactions have attracted the attention of organic chemists to prepare new compounds with diverse stereochemistry. Radical-induced methods mostly follow atom economical principles. Tin-based radical annulation method is the most common and widely used procedure for the synthesis of a wide range of organic compounds with medicinal significance. In this review, we report recent stereoselective tin-mediated radical cyclization reactions. The versatility of tinbased reagents in the cyclization process as reported herein will encourage chemists to construct many other molecules of interest following the principles involved in these reactions.

Keywords: Carbon-carbon bond, tin, annulation, radical cyclization, stereochemistry, radical mediated.

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