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ISSN (Print): 1872-2105
ISSN (Online): 2212-4020

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Research Article

Green Synthesis of Silver Nanoparticles Using Datura metel Flower Extract Assisted by Ultrasound Method and Its Antibacterial Activity

Author(s): Is Fatimah*, Habibi Hidayat, Bambang Nugroho and Saddam Husein

Volume 17, Issue 1, 2023

Published on: 12 January, 2022

Page: [68 - 73] Pages: 6

DOI: 10.2174/1872210515666210614165105

Price: $65

Abstract

Background: Green synthesis method of nanoparticles has been developed for several years. Besides providing environmental-friendly process, green synthesis of nanoparticles using plant extract provides synergistic effect of the secondary metabolite in such antibiotic activity. The study with an intensification process in nanoparticles formation is also gaining great attention. This research deals with the green synthesis of silver nanoparticles using Datura metel flower extract for the antibacterial agent. The use of ultrasound-assisted method for the synthesis was investigated.

Methods: Synthesis of silver nanoparticles (AgNPs) using Datura metel flower extract under ultrasound- assisted method has been conducted. Evaluation of the successful synthesis was done using UV-visible spectrophotometry, particle size analyzer, x-ray diffraction, and transmission electron microscopy. The prepared AgNPs were tested as an antibacterial against S. aureus, K. pneumoniae, S. pyogenes, and E. coli.

Results: The ultrasound-assisted synthesis of AgNPs produces particles ranging from 25-70 nm in size; meanwhile, the reflux method demonstrated the size of 50-170 nm. These particles size represents the effect on the antibacterial activity as the ultrasound-assisted synthesized Ag NPs have higher inhibition zone towards all tested bacteria. Subsequently, these data presented the applicability of Ag NPs synthesis using an ultrasound method as a potential candidate for biomedical applications.

Conclusion: The profile of UV-Visible spectra and particle size analyses demonstrated the applicability of the ultrasound technique to produce a smaller size of the nanoparticles with higher antibacterial activity.

Keywords: AgNPs, antibacterial agent, Datura metel, green synthesis, ultrasound, silver nanoparticles.

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