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Current Medical Imaging


ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Perilesional Lymph Node Swelling Might be a Radiologic Clue for Appendiceal Schwannoma: A Case Report

Author(s): Kunihito Suzuki*, Kazuhiro Saito, Takafumi Yamada, Elly Arizono, Hidehiro Kumita, Kenta Kasahara, Kenji Katsumata, Koichiro Tasaki, Jun Matsubayashi and Toshitaka Nagao

Volume 17 , Issue 10 , 2021

Published on: 13 July, 2021

Page: [1266 - 1270] Pages: 5

DOI: 10.2174/1573405617666210608152957

open access plus


Background: Gastrointestinal schwannoma is not a common type of tumor, and lesions originating from the appendix are extremely rare. Herein, we report a patient with appendiceal schwannoma characterized by lymph node swelling.

Case Report: A 67-year-old male patient who had diabetes complained of weight loss. A computed tomography scan revealed a mass in the right side of the pelvic cavity. Moreover, a contrast-enhanced computed tomography scan showed perilesional lymph node swelling measuring up to 28 mm. A low-intensity mass was observed on T1-weighted imaging, heterogeneous high-intensity mass on T2-weighted imaging, and restricted diffusion on diffusion-weighted imaging. There were no abnormal findings on colonoscopy. Based on a preoperative examination, a differential diagnosis of either appendiceal schwannoma, carcinoid, or gastrointestinal stromal tumor was considered. During surgery, a large appendiceal mass and multiple swollen perilesional lymph nodes were observed. Therefore, ileocecal resection and D3 lymph node dissection were performed. Pathological and immunohistochemical analyses confirmed the diagnosis of appendiceal schwannoma. There were numerous swollen lymph nodes in the mesenteric region. The lymph nodes revealed reactive lymphoid hyperplasia, with enlarged follicles of various sizes and shapes with an irregular distribution. Almost all lymphocytes, except those at the germinal centers, were small.

Conclusion: Gastrointestinal schwannoma is characterized by lymph node swelling. Appendiceal schwannoma may have characteristics, including peritumoral lymph node swelling, similar to other types of gastrointestinal schwannoma such as that in the stomach. Thus, this characteristic can be a diagnostic clue for appendiceal schwannoma.

Keywords: Appendiceal schwannoma, schwannoma, appendiceal tumor, stomach, CT, MRI.

Graphical Abstract

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