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Current Pediatric Reviews

Editor-in-Chief

ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Review Article (Mini-Review)

Liver Transplantation in Children: An Overview of Organ Allocation and Surgical Management

Author(s): Chiara Grimaldi, Marco Spada and Giuseppe Maggiore*

Volume 17 , Issue 4 , 2021

Published on: 04 June, 2021

Page: [245 - 252] Pages: 8

DOI: 10.2174/1573396317666210604111538

Price: $65

Abstract

Liver transplantation is the standard treatment for children with end-stage liver disease, primary hepatic neoplasms, or liver-localized metabolic defects. Perioperative mortality is almost absent, and long-term survival exceeds 90%. Organ shortage is managed thanks to advances in organ retrieval techniques; living donation and partial liver transplantation almost eliminated waiting list mortality, thus leading to expanding indications for transplantation. The success of pediatric liver transplantation depends on the prompt and early referral of patients to transplant Centers and on the close and integrated multidisciplinary collaboration between pediatricians, hepatologists, surgeons, intensivists, oncologists, pathologists, coordinating nurses, psychologists, and social workers.

Keywords: Liver transplantation, children, liver graft, living-donor liver transplantation, hepatic neoplasms, organ shortage.

Graphical Abstract

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