Work on human immortalized cell lines is not considered research on human subjects, but does involve biohazards. It has also been estimated that about 80% of human cell lines are the kind of cells that they are expected. Cells that are cultured directly from a subject are referred to as primary cells. Clonetics is the term can be used to describe Human Immortalized Cell Lines. Using Clonetics, the process of drug discovery and development can be accelerated. It is expected to contribute to drug development in metabolic diseases. These can be successfully used in many medical treatments.