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CNS & Neurological Disorders - Drug Targets

Editor-in-Chief

ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

Review Article

Role of Natural Plant Products Against Alzheimer’s Disease

Author(s): Himanshi Varshney and Yasir Hasan Siddique*

Volume 20 , Issue 10 , 2021

Published on: 20 April, 2021

Page: [904 - 941] Pages: 38

DOI: 10.2174/1871527320666210420135437

Price: $65

Abstract

Alzheimer’s Disease (AD) is one of the major neurodegenerative disorders. Deposition of amyloid fibrils and tau protein is associated with various pathological symptoms. Currently, limited medication is available for AD treatment. Most of the drugs are basically cholinesterase inhibitors and associated with various side effects. Natural plant products have shown potential as a therapeutic agent for the treatment of AD symptoms. A variety of secondary metabolites such as flavonoids, tannins, terpenoids, alkaloids, and phenols are used to reduce the progression of the disease. Plant products have fewer or no side effects and are easily available. The present review gives a detailed account of the potential of natural plant products against AD symptoms.

Keywords: Alzheimer's disease, natural plant products, pathogenesis, treatment, AD symptoms, secondary metabolites.

Graphical Abstract

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