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Current Drug Metabolism


ISSN (Print): 1389-2002
ISSN (Online): 1875-5453


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Author(s): Nico P.E. Vermeulen

Volume 22 , Issue 3 , 2021

Published on: 18 March, 2021

Page: [163 - 163] Pages: 1

DOI: 10.2174/138920022203210318122829

Autrup H, Barile FA, Berry SC, et al. Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs? Toxicology Letters 2020; 331: 259-64.
Koenderink JB, van den Heuvel JJMW, Bilos A, Vredenburg G, Vermeulen NPE, Russel FGM. Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates. Archives of Toxicology 2020; 94: 3027-32.
Rifai EA, Van Dijk M, Vermeulen NPE, Yanuar A, Geerke DP. A Comparative Linear Interaction Energy and MM/PBSA Study on SIRT1-Ligand Binding Free Energy Calculation. Journal of Chemical Information and Modeling 2019; 59: 4018-33.
Dekker SJ, Dohmen F, Vermeulen NPE, Commandeur JNM. Characterization of kinetics of human cytochrome P450s involved in bioactivation of flucloxacillin: inhibition of CYP3A-catalysed hydroxylation by sulfaphenazole. British Journal of Pharmacology 2019; 176: 466-77.
Ortega Ugalde S, de Koning CP, Wallraven K, et al. Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners. Applied Microbiology and Biotechnology, 2018; 102: 9231-42.
Huseinovic A, Dekker SJ, Boogaard B, Vermeulen NPE, Kooter JM, Vos JC. Acetaminophen reduces the protein levels of high affinity amino acid permeases and causes tryptophan depletion. Amino Acids 2018; 50: 1377-90.
Zhang Y, Wijaya L, Dekker SJ, Vermeulen NPE, Commandeur JNM. High-performance liquid chromatography-based assay for glutathione transferase theta 2 activity: Application to characterize interindividual variability in human liver fractions. Journal of Pharmaceutical and Biomedical Anal ysis 2018; 156: 181-8.
Luirink RA, Dekker SJ, Capoferri L, et al. A combined computational and experimental study on selective flucloxacillin hydroxylation by cytochrome P450 BM3 variants. Journal of Inorganic Biochemistry 2018; 184: 115-22.
Zhang Y, den Braver-Sewradj SP, den Braver MW, et al. Glutathione S-transferase P1 protects against Amodiaquine Quinoneimines-induced cytotoxicity but does not prevent activation of endoplasmic reticulum stress in HepG2 cells. Frontiers in Pharmacology 2018; 9.
Lazarska KE, Dekker SJ, Vermeulen NPE, Commandeur JNM. Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism. Toxicology Letters 2018; 284: 70-8.

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