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Mini-Reviews in Organic Chemistry


ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

Seco-Tetracyclic and Seco-Pentacyclic Triterpenoids from Nature: Phytochemistry, Biological Activity: A Review

Author(s): Yingkai Liu, Yuqing Jian, Mengru Cao, Bin Wang, Yixing Qiu, Hanwen Yuan, Xudong Zhou, Bin Li, Wenbing Sheng, Caiyun Peng, Zaiqi Zhang* and Wei Wang*

Volume 19, Issue 2, 2022

Published on: 11 March, 2021

Page: [188 - 230] Pages: 43

DOI: 10.2174/1570193X18666210311164309

Price: $65


Seco-tetracyclic and seco-pentacyclic triterpenoids are a special class of triterpenoids with ring/rings cleaved on the original skeleton structures. A class of important triterpene derivatives, secotetracyclic and seco-pentacyclic triterpenoids, have long stimulated the interest and attention of botanists and natural products chemists. There is no systematic and comprehensive review for them. This review is focused on the phytochemical investigations and biological activities of seco-tetracyclic and seco-pentacyclic triterpenoids from nature, covering the literature from 2000-2019. This review describes 310 seco-tetracyclic and 139 seco-pentacyclic triterpenoids discovered from 154 species belong to 97 genera, which cover the chemical structures, types, sources, and bioactivities of compounds. The literature from 2000-2019 is reviewed and 208 references are cited.

Keywords: Seco-tetracyclic triterpenoids, Seco-pentacyclic triterpenoids, phytochemistry, chemical structure, bioactivity, triterpenoids.

Graphical Abstract
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