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Coronaviruses

Editor-in-Chief

ISSN (Print): 2666-7967
ISSN (Online): 2666-7975

Review Article

COVID-19 Pandemic: An Overview of its Origin, Current Status, and Ongoing Clinical Trials

(E-pub Ahead of Print)
Author(s): Kartik Majila, Seema Lal and Mohammad Faiz Ahmad*

Article ID: e130921191206

DOI: 10.2174/2666796702666210208143656

Abstract

The COVID19 pandemic is raging across the globe, with the total active cases increasing each day. Globally over 63 million COVID-19cases and more than 1.4 million deaths have been reported to WHO. Throughout the world, academicians, clinicians and scientists are working tirelessly on developing a treatment to combat this pandemic. The origin of novel SARS CoV2 virus still remains foggy but is believed to have originated from a bat coronavirus RaTG13 with which it shares approximately 96% sequence similarity. In the present review, the authors have provided an overview of the COVID-19 pandemic, epidemiology, transmission, developments related to diagnosis, drugs and vaccines, along with the genetic diversity and lifecycle of the SARS CoV2 based on the current studies and information available.

Keywords: COVID-19, SARS CoV2, ACE2, spike, diagnosis, vaccine.


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