Recent Trend in the Chemistry of Triazolopyrimidines and their Applications

Title:Recent Trend in the Chemistry of Triazolopyrimidines and their Applications

Volume: 18 Issue: 8

Author(s): Mounir A. Salem, Mohamed S. Behalo and Rizk E. Khidre*

Affiliation:

• Chemistry Department, Faculty of Science, Jazan University, Jazan,Saudi Arabia

Keywords: Triazolopyrimidine, pyrimidine, triazole, synthesis, heterocycles, pharmacological activities.

Abstract: This review deals with the synthetic methods, chemical reactions, and applications of triazolopyrimidine derivatives. The synthetic methods and chemical reactions are subdivided into groups according to the junction between triazole and pyrimidine moieties for instance [1,2,4]triazolo[1,5- a]pyrimidine, [1,2,4]triazolo[1,5-c]pyrimidine, [1,2,3]triazolo[1,5-a]pyrimidine, [1,2,3]triazolo[1,5- c]pyrimidine, [1,2,4]triazolo[4,3-c]pyrimidine, and [1,2,4]triazolo[4,3-a]pyrimidine. Pharmacological activity of triazolopyrimidins is also reported.

Cite this article as:

Salem A. Mounir , Behalo S. Mohamed and Khidre E. Rizk *, Recent Trend in the Chemistry of Triazolopyrimidines and their Applications, Mini-Reviews in Organic Chemistry 2021; 18(8) . https://dx.doi.org/10.2174/1570193X18666210203155358