This review article mainly focuses on the revolution of the synthesis of gold nanoplatform from the previous era to the present era. Initially, the gold nanoplatform was widely used by the electrical and electronic industries for their products due to its remarkable properties, such as large surface volume, redox activity, fluorescence quenching, and optical-electronic properties. In this era, due to the invention of localised surface plasmonic resonance, optoacoustic, photothermal and theragnostic characteristics of the gold nanoplatforms and their application in biosensors and various diagnostic methods, the pharmaceutical and biotechnological companies have started showing their interest in manufacturing gold nanoplatforms for their new product development. This colloidal dispersion is synthesized in various forms, such as a gold nanoparticle, gold nanoplatform, plasmonic gold nanoparticle, amphiphilic gold nanoparticle, and gold nanocrystal. This review article describes various methods for preparation of gold nanoplatforms with different size, shape, and physiobiological properties and their applications in different fields.