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Mini-Reviews in Organic Chemistry


ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Review Article

A Short Review on the Synthesis of 1,2,4-Triazine Derivatives as Bioactive Compounds

Author(s): Heba E. Hashem*

Volume 18, Issue 8, 2021

Published on: 22 January, 2021

Page: [1127 - 1133] Pages: 7

DOI: 10.2174/1570193X18666210122154419

Price: $65


Triazines and their oxo derivatives are a representative class of heterocyclic compounds which have attracted great attention in organic synthesis and medicinal chemistry as they have been associated with a broad range of pharmacological activities. 1,2,4-Triazines and their oxo derivatives exhibit a broad range of biological activities, including antimicrobial, antifungal, anticancer, antiinflammatory, besides having importance in the dyes and pesticides field. This review presents the different methods of the synthesis of triazine/one derivatives. Also, this literature surveys the different effects of these compounds in pharmaceuticals.

Keywords: 1, 2, 4-Triazine, fused triazine, heterocycles, biological activity, synthesis, oxo derivatives.

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