Abstract
Breast cancer is the most common type of malignancy affecting women worldwide and also stands being the most diagnosed one. Mammography is considered as the golden standard for diagnosis but there are high chances that it can give false- negative as well as false-positive test results. Finding cost-effective, readily available diagnosis along with increased sensitivity as well as specificity is the need right now to decrease the mortality as well as the morbidity rate. The application of biomarkers to clinical use has paved the way for a better prognosis, diagnosis, detection, screening and better clinical results. The efficacy of the treatment is enhanced. Biomarkers are known to cause an advancement in breast cancer study and are expected to improve the quality of life in patients. Not only tissue biomarkers but serum and circulating biomarkers are also of significance in patients. This review highlights the particulars about the current use and application of biomarkers in an effective prognosis, detection, treatment of the breast cancer and also the ones which are currently being studied under clinical trials and have the potential to be advantageous and more specific in the future.
Keywords: Breast cancer, biomarkers, diagnosis, global, cytotoxic, screening.
Current Pharmaceutical Design
Title:Focus on the Multimodal Role of Biomarkers in Breast Cancer
Volume: 27 Issue: 35
Author(s): Damanpreet K. Lang, Ankita Sood, Rajwinder Kaur*, Rashmi Arora and Tapan Behl*
Affiliation:
- Chitkara College of Pharmacy, Chitkara University, Punjab,India
- Chitkara College of Pharmacy, Chitkara University, Punjab,India
Keywords: Breast cancer, biomarkers, diagnosis, global, cytotoxic, screening.
Abstract: Breast cancer is the most common type of malignancy affecting women worldwide and also stands being the most diagnosed one. Mammography is considered as the golden standard for diagnosis but there are high chances that it can give false- negative as well as false-positive test results. Finding cost-effective, readily available diagnosis along with increased sensitivity as well as specificity is the need right now to decrease the mortality as well as the morbidity rate. The application of biomarkers to clinical use has paved the way for a better prognosis, diagnosis, detection, screening and better clinical results. The efficacy of the treatment is enhanced. Biomarkers are known to cause an advancement in breast cancer study and are expected to improve the quality of life in patients. Not only tissue biomarkers but serum and circulating biomarkers are also of significance in patients. This review highlights the particulars about the current use and application of biomarkers in an effective prognosis, detection, treatment of the breast cancer and also the ones which are currently being studied under clinical trials and have the potential to be advantageous and more specific in the future.
Export Options
About this article
Cite this article as:
Lang K. Damanpreet, Sood Ankita , Kaur Rajwinder *, Arora Rashmi and Behl Tapan *, Focus on the Multimodal Role of Biomarkers in Breast Cancer, Current Pharmaceutical Design 2021; 27 (35) . https://dx.doi.org/10.2174/1381612827999210111185213
DOI https://dx.doi.org/10.2174/1381612827999210111185213 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
Call for Papers in Thematic Issues
Advances in the Molecular Pathogenesis of Inflammatory Bowel Disease.
This thematic issue will emphasize the recent breakthroughs in the mechanisms of Inflammatory bowel disease (IBD) pathogenesis and devotes some understanding of both Crohn’s and ulcerative colitis. It is expected to include studies about cellular and genetic aspects, which help to precipitate the disease, and the immune system-gut microbiome relations ...read more
Blood-based biomarkers in large-scale screening for neurodegenerative diseases
Disease biomarkers are necessary tools that can be employed in several clinical context of use (COU), ranging from the (early) diagnosis, prognosis, and prediction, to monitoring of disease state and/or drug efficacy. Regarding neurodegenerative diseases, in particular Alzheimer’s disease (AD), a battery of well-validated biomarkers are available, such as cerebrospinal ...read more
Current Pharmaceutical challenges in the treatment and diagnosis of neurological dysfunctions
Neurological dysfunctions (MND, ALS, MS, PD, AD, HD, ALS, Autism, OCD etc..) present significant challenges in both diagnosis and treatment, often necessitating innovative approaches and therapeutic interventions. This thematic issue aims to explore the current pharmaceutical landscape surrounding neurological disorders, shedding light on the challenges faced by researchers, clinicians, and ...read more
Diabetes mellitus: advances in diagnosis and treatment driving by precision medicine
Diabetes mellitus (DM) is a chronic degenerative metabolic disease with ever increasing prevalence worldwide which is now an epidemic disease affecting 500 million people worldwide. Insufficient insulin secretion from pancreatic β cells unable to maintain blood glucose homeostasis is the main feature of this disease. Multifactorial and complex nature of ...read more

- Author Guidelines
- Bentham Author Support Services (BASS)
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Selective Elevation of Circulating CCL2/MCP1 Levels in Patients with Longstanding Post-vaccinal Macrophagic Myofasciitis and ASIA
Current Medicinal Chemistry Choosing between Targeted Therapies for Rheumatoid Arthritis Patients: The Oncology Perspective
Current Rheumatology Reviews The Biological and Clinical Activity of Anti-Malarial Drugs In Autoimmune Disorders
Current Rheumatology Reviews Medicinal Plants and Atherosclerosis: A Review on Molecular Aspects
Current Pharmaceutical Design Uveitis in Rheumatic Diseases
Current Rheumatology Reviews Amyloidosis and Auto-Inflammatory Syndromes
Current Drug Targets - Inflammation & Allergy Anesthetic Cardioprotection: The Role of Adenosine
Current Pharmaceutical Design The Biology and Therapeutic Potential of the DDAH/ADMA Pathway
Current Pharmaceutical Design Free Radicals in Diseases and Potential Role of Phytoconstituents-A Cause with Emerging Importance
Current Chemical Biology Application of Resveratrol in Diabetes: Rationale, Strategies and Challenges
Current Molecular Medicine Vascular Endothelial Growth Factor (VEGF) Signaling in Tumour Vascularization: Potential and Challenges
Current Vascular Pharmacology Transgenic Models in Allergic Responses
Current Drug Targets Ocular Inflammatory Diseases: Molecular Pathogenesis and Immunotherapy
Current Molecular Medicine Future Directions of Maintenance Therapy in ANCA-associated Vasculitis
Current Medicinal Chemistry Meet Our Editorial Board Member:
Current Rheumatology Reviews PCSK9 Inhibition - A Novel Mechanism to Treat Lipid Disorders?
Current Pharmaceutical Design Vasculitis: Decade in Review
Current Rheumatology Reviews The Use of Radioactive Iodine in the Management of Hyperthyroidism in Children
Current Drug Targets - Immune, Endocrine & Metabolic Disorders Multiple Faceted Roles of Cocaine in Potentiation of HAND
Current HIV Research A Very Rare Cerebral Complication of Chemotherapy in a Young Girl: A Difficult Diagnosis
Current Drug Safety