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Current Topics in Medicinal Chemistry


ISSN (Print): 1568-0266
ISSN (Online): 1873-4294


Looking Beyond DNA as the Target of Inorganic Chemotherapy Agents: The Key Role of Protein Metalation and Metal Homeostasis

Author(s): Tiziano Marzo and Diego La Mendola*

Volume 21 , Issue 1 , 2021

Published on: 11 December, 2020

Page: [3 - 5] Pages: 3

DOI: 10.2174/156802662101201211094545

Johnstone, T.C.; Suntharalingam, K.; Lippard, S.J. The next generation of platinum drugs: targeted pt(ii) agents, nanoparticle delivery, and pt(iv) prodrugs. Chem. Rev., 2016, 116(5), 3436-3486.
Marzo, T.; Ferraro, G.; Merlino, A.; Messori, L. Protein metalation by inorganic anticancer drugs.In:Encyclopedia of Inorganic and Bioinorganic Chemistry; Wiley: Hoboken, 2020.
Miodragović, D.; Merlino, A.; Swindell, E.P.; Bogachkov, A.; Ahn, R.W.; Abuhadba, S.; Ferraro, G.; Marzo, T.; Mazar, A.P.; Messori, L.; O’Halloran, T.V. Arsenoplatin-1 is a dual pharmacophore anticancer agent. J. Am. Chem. Soc., 2019, 141(16)
Merlino, A.; Marzo, T.; Messori, L. Protein metalation by anticancer metallodrugs: a joint esi ms and xrd investigative strategy. Chem.- A Eur. J, 2017, 23(29)
La Mendola, D.; Giacomelli, C.; Rizzarelli, E. Intracellular bioinorganic chemistry and cross talk among different -omics. Curr. Top. Med. Chem., 2016, 16(27), 3103-3130.
Kilari, D.; Guancial, E.; Kim, E.S. Role of copper transporters in platinum resistance. World J. Clin. Oncol., 2016, 7(1), 106.
Naletova, I.; Cucci, L.M.; D’Angeli, F.; Anfuso, C.D.; Magrì, A.; La Mendola, D.; Lupo, G.; Satriano, C. A tunable nanoplatform of nanogold functionalised with angiogenin peptides for anti-angiogenic therapy of brain tumours. Cancers (Basel), 2019, 11(9), 1322.

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