Generic placeholder image

Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

General Research Article

Selective Optosensing of Aminoimidazo-Azaarenes (AIAs) by CdSe/ZnS Quantum Dots-embedded Molecularly Imprinted Silica Gel

Author(s): Dan Qiao, Qiliang Deng* and Shuo Wang*

Volume 17, Issue 7, 2021

Published on: 07 December, 2020

Page: [1027 - 1036] Pages: 10

DOI: 10.2174/1573411017666201208091423

Abstract

Background: The approach for the determination of aminoimidazo-azaarenes (AIAs) is urgently required due to their mutagenic activity and potential carcinogenicity. For this purpose, a CdSe/ZnS quantum dots (CdSe/ZnS QDs)-embedded molecularly imprinted silica gel with high selectivity and sensitivity was successfully prepared and applied to analyze such target.

Methods: Herein, CdSe/ZnS QDs acted as the fluorescent probe, and molecularly imprinted silica gel as a recognition probe was synthesized on the surface of QDs via sol-gel method. 2- Aminobenzimidazole, which has a similar structure with AIAs, as well as low cost and low toxicity, was selected as the dummy template.

Results: The material has a high imprinting factor (IF=6.15); the linear range of CdSe/ZnS@MIP as a fluorescent sensing material for AIAs is 0.5-20.0 μg L-1 with the limit of detection (LOD) of 0.25 μg L-1 (3σ/s). Moreover, the fluorescent materials have been further applied to determine AIAs in beef floss and grilled fish fillet with satisfactory recoveries (82.8-110.8 %), and the relative standard deviation (RSD) is < 5.5%.

Conclusion: The proposed CdSe/ZnS QDs-embedded molecularly imprinted silica gel can be used to easily and selectively detect AIAs.

Keywords: Heterocyclic aromatic amines, fluorescence sensor, CdSe/ZnS quantum dots, molecularly imprinted silica gel, molecular imprinting, aminoimidazo-azaarenes.

Graphical Abstract

© 2024 Bentham Science Publishers | Privacy Policy